414 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 49–96 of 414 trials
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin on Social Connectedness
Yale University
LonelinessGrief
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
Healthy Volunteers
Not Yet Recruiting·Phase 4·ketamine
Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Assiut University
Postoperative Pain
Not Yet Recruiting·N/A·ketamine
Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
China-Japan Friendship Hospital
Knee OsteoarthritisReplacement, KneeElective Surgical Patients+1 more
Not Yet Recruiting·Phase 4·ketamine
Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis
University of Mississippi Medical Center
Vaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 4·Other
Examining Analgesic Synergy and Efficacy in Trauma Care
Wake Forest University Health Sciences
Opioid Use Disorder
Not Yet Recruiting·N/A·ketamine
Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation
Stanford University
Chronic PainKetamine
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Not Yet Recruiting·N/A·Other
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
Hospital Clinic of Barcelona
Brugada Syndrome (BrS)Ventricular ArrhythmiaAnesthesia+1 more
Not Yet Recruiting·N/A·ketamine
Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study
Adriaan Dirk van der Wart
Post-Traumatic Stress Disorder
Not Yet Recruiting·N/A·ketamine
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
Ren Da
Biliary Tract DiseasesProcedural Sedation and Analgesia
Not Yet Recruiting·N/A·Other
Quality of Recovery-15 After Opioid-free Versus Opioid-based General Anesthesia in Major Urological Surgery
Jagiellonian University
Postoperative RecoveryAnesthesia, GeneralAnalgesics, Opioid+1 more
Not Yet Recruiting·Phase 2·Other
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
Massachusetts General Hospital
Opoid ManagmentPain Management
Not Yet Recruiting·Phase 4·ketamine
Biomarker-Guided Antidepressant Selection
Weill Medical College of Cornell University
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin as a Novel Therapy for Residual Anhedonia
NYU Langone Health
AnhedoniaEmotional Blunting
Not Yet Recruiting·Phase 2·psilocybin
Study of Psilocybin Under Anesthesia Controlled by EEG
Stanford University
Major Depression
Not Yet Recruiting·N/A·Other
Biomarker Discovery for Suicide Precision Circuit Therapeutics
Massachusetts General Hospital
Suicidal Thoughts and BehaviorsMajor Depressive Episode (MDE)
Not Yet Recruiting·Phase 2·ketamine
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
University of Michigan
HealthyCovert Consciousness
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 2·ketamine
Pilot Randomized Control Trial Comparing Oral Ketamine and Oral Oxycodone for Pain Control in Emergency Department Patients
Albany Medical College
Pain Management
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy as a Treatment for Depression
Washington University School of Medicine
Depression
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·N/A·MDMA
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls
University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·N/A·Other
Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder
Shanghai Mental Health Center
Major Depressive Disorder (MDD
Not Yet Recruiting·Phase 1·Other
Opioid-free Anesthesia and Postoperative Delirium
Qianfoshan Hospital
Postoperative DeliriumGastrointestinal Tumors
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·N/A·LSD
Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)
Northern Jiangsu People's Hospital
Cirrhosis, LiverSplenectomy; StatusRenal Function Abnormal+1 more
Not Yet Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine
A 2×2 Factorial Randomized Controlled Trial for ERCP
Gang Chen
Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Phase 2·ketamine
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Irma Fleming
PTSD and Trauma-related Symptoms
Not Yet Recruiting·Phase 1·DMT
Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy Subjects
GH Research Ireland Limited
Healthy Adult
Not Yet Recruiting·Phase 1·MDMA
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Resilient Pharmaceuticals
PharmacokineticsHepatic Impairment
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine
KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study
Helsinki University Central Hospital
Drug Drug Interaction
Not Yet Recruiting·N/A·Other
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
Zagazig University
Sedation During GI Endoscopy
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.