418 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 49–96 of 418 trials
Not Yet Recruiting·Phase 3·ketamine
Morphine or Ketamine for Analgesia
Columbia University
Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Phase 4·ketamine
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
New York State Psychiatric Institute
Major Depressive Disorder (MDD)
Not Yet Recruiting·N/A·Other
An International Federated Model for Wearable-derived Remote Longitudinal Motor Monitoring in Young Children With Spinal Muscular Atrophy Compared With Healthy Controls: Active-NBS Study (UK)
University of Oxford
Spinal Muscular Atrophy (SMA)
Not Yet Recruiting·Phase 1·psilocybin
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
PTSD
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·Phase 1·MDMA
MDMA Assisted Therapy for BN
Icahn School of Medicine at Mount Sinai
Bulimia Nervosa
Not Yet Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Not Yet Recruiting·Phase 2·psilocybin
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Not Yet Recruiting·Phase 4·Other
Examining Analgesic Synergy and Efficacy in Trauma Care
Wake Forest University Health Sciences
Opioid Use Disorder
Not Yet Recruiting·Phase 4·ketamine
Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities
University of Sao Paulo
Suicide PreventionKetamineCrisis Response Plan
Not Yet Recruiting·Phase 2·psilocybin
Subjective Experience Following Psilocybin
University of Calgary
Investigating the Importance of the Subjective Psychedelic Experience
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
VA Office of Research and Development
Post Traumatic Stress DisorderAlcohol Use Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Phase 2·ketamine
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Irma Fleming
PTSD and Trauma-related Symptoms
Not Yet Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 1·DMT
Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy Subjects
GH Research Ireland Limited
Healthy Adult
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers
Nautilus Sanctuary
Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·Phase 1·MDMA
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Resilient Pharmaceuticals
PharmacokineticsHepatic Impairment
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine
KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study
Helsinki University Central Hospital
Drug Drug Interaction
Not Yet Recruiting·Phase 4·ketamine
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
University of Missouri-Columbia
Spine Surgery
Not Yet Recruiting·N/A·Other
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
Zagazig University
Sedation During GI Endoscopy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Post Traumatic Stress DisorderPTSDChronic PTSD
Not Yet Recruiting·Phase 3·Other
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
Centre Hospitalier Universitaire, Amiens
Intravenous LidocaineLaparoscopic SurgeryPost Operative Recovery+1 more
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
Major Depressive Disorder (MDD)Alcohol Use Disorder (AUD)
Not Yet Recruiting·Early Phase 1·ketamine
The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.
National and Kapodistrian University of Athens
Opioid-Refractory Chronic Cancer-Related Pain
Not Yet Recruiting·Phase 2·ketamine
Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.
Fondation Lenval
TraumatologyWounds and InjuryFractures Bone+4 more
Not Yet Recruiting·N/A·Other
Ketodex Versus Ketofol in Adolescent Gastrointestinal Endoscopy
Giresun University
Procedural SedationGastrointestinal Endoscopy
Not Yet Recruiting·N/A·ketamine
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
Sohag University
Postoperative Sore Throat
Not Yet Recruiting·N/A·ketamine
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Nanjing First Hospital, Nanjing Medical University
Post Induction Hypotension
Not Yet Recruiting·Phase 4·ketamine
Ketamine in Central Sensitization
University Hospitals Cleveland Medical Center
EndometriosisChronic Pelvic Pain
Not Yet Recruiting·N/A·Other
Influence of Therapeutic Failure on the Psychosocial Experience in Multiple Sclerosis
University Hospital, Caen
Multiple Sclerosis
Not Yet Recruiting·Phase 2·ketamine
Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement
University of California, San Diego
Opioid Use Disorder
Not Yet Recruiting·Phase 3·ketamine
Optimal Timing of Ketamine Initiation for SCD Pain
Boston Children's Hospital
Sickle Cell DiseaseSickle Cell Crisis
Not Yet Recruiting·Phase 3·ketamine
Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy
Assiut University
Pain
Not Yet Recruiting·Phase 3·ketamine
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
Zagazig University
Postoperative AnalgesiaPostoperative Pain Management
Not Yet Recruiting·N/A·ketamine
Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·N/A·ketamine
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression
Chinese PLA General Hospital
DepressionAnxietyS-ketamine+1 more
Not Yet Recruiting·Phase 2·psilocybin
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Stuttering
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
Oregon Health and Science University
Chronic Pelvic Pain
Not Yet Recruiting·Phase 1·ketamine
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
Liaquat National Hospital & Medical College
SedationPreoperative Anxiety Experienced by the Pediatric PatientAnxiolytic Effect+1 more
Not Yet Recruiting·N/A·Other
Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries With Cardiopulmonary Bypass in Enhanced Recovery After Surgeries
Ain Shams University
CABGDexmedetomidineKetamine+2 more
Not Yet Recruiting·Phase 1·Other
Magnesium Sulfate in Pediatric Burn Dressing Changes
Hennepin Healthcare Research Institute
Pediatric Burns
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.