417 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 49–96 of 417 trials
Not Yet Recruiting·Phase 2·MDMA
MDMA Therapy in Veterans With PTSD
Sunstone Medical
Post Traumatic Stress Disorder
Not Yet Recruiting·Early Phase 1·Other
Transition From Acute to Chronic Opioid Use and Chronic Pain
Jacques E. Chelly
Opioid Use Disorder
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Johns Hopkins University
Mood (Psychological Function)Well BeingMood+1 more
Not Yet Recruiting·Phase 2·Other
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
Massachusetts General Hospital
Opoid ManagmentPain Management
Not Yet Recruiting·Phase 2·psilocybin
Study of Psilocybin Under Anesthesia Controlled by EEG
Stanford University
Major Depression
Not Yet Recruiting·Phase 2·ketamine
Ketamine HCl Prolonged Release Oral Tablets for CRPS
University of Southern California
Complex Regional Pain Syndromes
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin as a Novel Therapy for Residual Anhedonia
NYU Langone Health
AnhedoniaEmotional Blunting
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Smokers With Chronic Pain
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
Healthy Volunteers
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psychedelic Effects in Healthy Volunteers
Not Yet Recruiting·N/A·Other
Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial
Centre Hospitalier Universitaire de Nice
Rotator Cuff InjuriesAnesthesia, GeneralArthroscopy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Brigham and Women's Hospital
Alcohol Use Disorder
Not Yet Recruiting·Phase 2·ketamine
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Joshua Rosenblat
Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Not Yet Recruiting·Phase 3·psilocybin
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms
Centre Hospitalier Universitaire de Nīmes
Alcohol Use DisorderDepressive SympotomsPsilocybin
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy as a Treatment for Depression
Washington University School of Medicine
Depression
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·N/A·MDMA
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls
University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 2·ketamine
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
University of Oklahoma
Head and Neck Cancer
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Therapy
Emory University
PTSD
Not Yet Recruiting·N/A·Other
Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder
Shanghai Mental Health Center
Major Depressive Disorder (MDD
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·N/A·Other
Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy
Fundacio Puigvert
AnesthesiaAnesthesia and Procedure Related Time IntervalsNephrectomy / Methods
Not Yet Recruiting·N/A·LSD
Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)
Northern Jiangsu People's Hospital
Cirrhosis, LiverSplenectomy; StatusRenal Function Abnormal+1 more
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
Lakshmi N Yatham
Bipolar II Depression
Not Yet Recruiting·Phase 1·Other
Opioid-free Anesthesia and Postoperative Delirium
Qianfoshan Hospital
Postoperative DeliriumGastrointestinal Tumors
Not Yet Recruiting·Phase 4·ketamine
Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts
New York State Psychiatric Institute
Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 4·ketamine
Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities
University of Sao Paulo
Suicide PreventionKetamineCrisis Response Plan
Not Yet Recruiting·Phase 2·psilocybin
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Yale University
DepressionParkinson's Disease (PD)
Not Yet Recruiting·Phase 3·ketamine
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Sunnybrook Health Sciences Centre
Treatment Resistant Depression
Not Yet Recruiting·Phase 1·MDMA
MDMA Assisted Therapy for BN
Icahn School of Medicine at Mount Sinai
Bulimia Nervosa
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Post Traumatic Stress DisorderPTSDChronic PTSD
Not Yet Recruiting·Phase 2·psilocybin
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
Kyle Greenway
Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine
A 2×2 Factorial Randomized Controlled Trial for ERCP
Gang Chen
Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine
Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery
Tanta University
ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·psilocybin
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Treatment-Resistant Depression
Not Yet Recruiting·Phase 2·ketamine
KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury
Irma Fleming
PTSD and Trauma-related Symptoms
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
Nantes University Hospital
Gambling Disorder
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Microdosing on Cognition, Mood and Quality of Life
Yale University
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
Not Yet Recruiting·Phase 1·DMT
Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy Subjects
GH Research Ireland Limited
Healthy Adult
Not Yet Recruiting·Phase 1·MDMA
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Resilient Pharmaceuticals
PharmacokineticsHepatic Impairment
Not Yet Recruiting·N/A·ketamine
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Aga Khan University
Breast CancerPain, ChronicPost Surgical Pain
Not Yet Recruiting·Phase 1·ketamine
KF2025#1 Trial: Ketamine, Cannabidiol and Cobicistat Interaction Study
Helsinki University Central Hospital
Drug Drug Interaction
Not Yet Recruiting·N/A·Other
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
Zagazig University
Sedation During GI Endoscopy
Not Yet Recruiting·Phase 3·Other
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
Centre Hospitalier Universitaire, Amiens
Intravenous LidocaineLaparoscopic SurgeryPost Operative Recovery+1 more
Browse by Condition
View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.