417 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1–48 of 417 trials
Enrolling by Invitation·Phase 4·ketamine
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
University of Missouri-Columbia
Spine Surgery
Enrolling by Invitation·N/A·ketamine
Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation
University of California, San Diego
Suicidal Ideation
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 1·psilocybin
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
PsilocybinMusic Intervention
Enrolling by Invitation·Phase 3·psilocybin
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Cybin IRL Limited
Major Depressive Disorder
Enrolling by Invitation·Phase 2·ketamine
Ketamine Effects on Learning In Eating Disorders
Amanda Downey, MD
Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Enrolling by Invitation·Phase 1·Other
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
Stanford University
Healthy Volunteers
Enrolling by Invitation·Phase 2·MDMA
High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·Phase 2·ketamine
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
University of Texas at Austin
Long COVID
Enrolling by Invitation·N/A·ketamine
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
Psyrin Inc.
Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·N/A·ketamine
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
University of Pittsburgh
Depression
Enrolling by Invitation·Phase 1·psilocybin
Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD
Centre for Addiction and Mental Health
Obsessive-Compulsive Disorder
Enrolling by Invitation·N/A·ketamine
Using Virtual Reality to Control the Audio-visual Inputs During Ketamine/Esketamine Treatment
Yale University
Depression
Enrolling by Invitation·Phase 2·MDMA
MDMA Plus Exposure Therapy for PTSD
Emory University
PTSD
Enrolling by Invitation·N/A·ketamine
Long Term Follow Up KET-PD
Yale University
Parkinson's DiseaseDepression
Enrolling by Invitation·Phase 4·ketamine
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Brigham and Women's Hospital
Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine
Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements
Kernel
DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·Other
Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
University of Kansas Medical Center
AnesthesiaTubal Ligation
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·ketamine
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
Medical University of Gdansk
Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Enrolling by Invitation·N/A·ketamine
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Erasmus Medical Center
Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
Vanderbilt University Medical Center
Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 3·Other
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
Hospital for Special Surgery, New York
Lumbar Disc HerniationLumbar Disc DiseaseLumbar Radiculopathy
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Not Yet Recruiting·Phase 2·psilocybin
Group PACBT for Depression
University of California, Los Angeles
Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Not Yet Recruiting·Phase 2·ketamine
Adjunctive Oral KET-AD Capsules in Treatment Resistant Bipolar Depression
Neurocentrx Pharma Pty Ltd
Treatment Resistant Bipolar Depression
Not Yet Recruiting·Phase 3·ketamine
KetAmine and Recovery After Mechanical VentilAtion ( KARMA )
Assistance Publique - Hôpitaux de Paris
Critical Illness
Not Yet Recruiting·Phase 2·MDMA
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
Nautilus Sanctuary
Post-Traumatic Stress DisorderAdjustment Disorders
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin for Treatment of OCD-2
Francisco A Moreno
Obsessive - Compulsive Disorder
Not Yet Recruiting·N/A·Other
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
Ente Ospedaliero Ospedali Galliera
FrailyAbdominal SurgeryPostoperative Cognitive Dysfunction (POCD)
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
Gabriella Gobbi
Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
University Hospital, Toulouse
Infusion of Ketamine in Severe Borderline Personality DisorderBorderline Personality Disorder (BPD)
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·Phase 3·ketamine
Morphine or Ketamine for Analgesia
Columbia University
Abdominal PainIsolated Extremity FracturePain+1 more
Not Yet Recruiting·Phase 2·psilocybin
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
COMPASS Pathways
PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more
Not Yet Recruiting·Phase 1·psilocybin
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Manoj Doss
Healthy
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Phase 4·Other
Examining Analgesic Synergy and Efficacy in Trauma Care
Wake Forest University Health Sciences
Opioid Use Disorder
Not Yet Recruiting·N/A·ketamine
Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation
Stanford University
Chronic PainKetamine
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Not Yet Recruiting·N/A·Other
Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome
Hospital Clinic of Barcelona
Brugada Syndrome (BrS)Ventricular ArrhythmiaAnesthesia+1 more
Not Yet Recruiting·N/A·ketamine
Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study
Adriaan Dirk van der Wart
Post-Traumatic Stress Disorder
Not Yet Recruiting·Phase 1·LSD
Shortened LSD Intervention for Major Depressive Disorder
Johns Hopkins University
Major Depression ModerateMajor Depression SevereMajor Depression
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.