418 Recruiting Now
Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Showing 1–48 of 418 trials
Enrolling by Invitation·N/A·ketamine
Psychotherapy Combined With Intranasal Esketamine for the Treatment of Suicidal Ideation
University of California, San Diego
Suicidal Ideation
Enrolling by Invitation·N/A·psilocybin
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
University of Geneva, Switzerland
Major Depressive Disorder (MDD)
Enrolling by Invitation·Phase 1·psilocybin
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
Johns Hopkins University
PsilocybinMusic Intervention
Enrolling by Invitation·Phase 3·psilocybin
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Cybin IRL Limited
Major Depressive Disorder
Enrolling by Invitation·Phase 2·ketamine
Ketamine Effects on Learning In Eating Disorders
Amanda Downey, MD
Anorexia NervosaAtypical Anorexia Nervosa
Enrolling by Invitation·Phase 1·psilocybin
Psilocybin With Intracranial Neural Sensing
Joshua Woolley, MD, PhD
Chronic Pain
Enrolling by Invitation·Phase 1·Other
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
Stanford University
Healthy Volunteers
Enrolling by Invitation·Phase 2·MDMA
High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD
ARQ National Psychotrauma Centre
Posttraumatic Stress Disorder (PTSD)
Enrolling by Invitation·Phase 2·ketamine
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
University of Texas at Austin
Long COVID
Enrolling by Invitation·N/A·ketamine
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
Psyrin Inc.
Obsessive Compulsive Disorder (OCD)Bipolar DisordersMajor Depressive Disorder+2 more
Enrolling by Invitation·N/A·ketamine
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
University of Pittsburgh
Depression
Enrolling by Invitation·N/A·ketamine
Using Virtual Reality to Control the Audio-visual Inputs During Ketamine/Esketamine Treatment
Yale University
Depression
Enrolling by Invitation·Phase 2·MDMA
MDMA Plus Exposure Therapy for PTSD
Emory University
PTSD
Enrolling by Invitation·N/A·ketamine
Long Term Follow Up KET-PD
Yale University
Parkinson's DiseaseDepression
Enrolling by Invitation·Phase 4·ketamine
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Brigham and Women's Hospital
Acute Suicidal Depression (ASD)
Enrolling by Invitation·N/A·ketamine
Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements
Kernel
DepressionMajor Depressive Disorder
Enrolling by Invitation·N/A·Other
Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
University of Kansas Medical Center
AnesthesiaTubal Ligation
Enrolling by Invitation·N/A·psilocybin
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Felix Mueller
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Enrolling by Invitation·N/A·ketamine
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
Medical University of Gdansk
Major Depressive DisorderPost Traumatic Stress DisorderObsessive-Compulsive Disorder+3 more
Enrolling by Invitation·N/A·ketamine
Observational Study of Ketamine Infusions for the Treatment of Chronic Pain
Theresa Lii
Chronic Pain
Enrolling by Invitation·N/A·ketamine
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Erasmus Medical Center
Complex Regional Pain SyndromesCRPS (Complex Regional Pain Syndromes)
Enrolling by Invitation·N/A·ketamine
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
Vanderbilt University Medical Center
Post-Traumatic Stress DisorderAcute Respiratory Failure
Enrolling by Invitation·Phase 3·Other
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
Hospital for Special Surgery, New York
Lumbar Disc HerniationLumbar Disc DiseaseLumbar Radiculopathy
Enrolling by Invitation·Phase 4·ketamine
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Mayo Clinic
Brachial Plexus Injury
Not Yet Recruiting·Phase 2·psilocybin
Group PACBT for Depression
University of California, Los Angeles
Depression - Major Depressive DisorderPsilocybinCognitive Behavioral Therapy
Not Yet Recruiting·Phase 1·psilocybin
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
Gabriella Gobbi
Healthy ParticipantsPlacebo - ControlPsilocybin
Not Yet Recruiting·Phase 2·ketamine
Nebulized Ketamine Plus Standard Care vs. Standard Care Alone in Moderate to Severe Asthma Exacerbations
Oman Medical Speciality Board
Asthma AcuteAsthma AttackAsthma Exacerbations
Not Yet Recruiting·N/A·Other
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
Ente Ospedaliero Ospedali Galliera
FrailyAbdominal SurgeryPostoperative Cognitive Dysfunction (POCD)
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
University of Calgary
Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
Indiana University
Treatment Resistant DepressionSubstance Use Disorders
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
NYU Langone Health
IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 1·LSD
Shortened LSD Intervention for Major Depressive Disorder
Johns Hopkins University
Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·Early Phase 1·Other
Transition From Acute to Chronic Opioid Use and Chronic Pain
Jacques E. Chelly
Opioid Use Disorder
Not Yet Recruiting·Phase 2·psilocybin
Anesthesia-Masked Psilocybin Therapy for Major Depression
Stanford University
Major Depression
Not Yet Recruiting·Phase 2·ketamine
Ketamine HCl Prolonged Release Oral Tablets for CRPS
University of Southern California
Complex Regional Pain Syndromes
Not Yet Recruiting·Phase 1·psilocybin
Psilocybin After Trauma Surgery for Pain
Trent Emerick
Pain ManagementPostoperative Pain
Not Yet Recruiting·Early Phase 1·psilocybin
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psychedelic Effects in Healthy Volunteers
Not Yet Recruiting·Phase 2·ketamine
Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers
National Center for Complementary and Integrative Health (NCCIH)
Healthy Volunteers
Not Yet Recruiting·Phase 1·psilocybin
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Not Yet Recruiting·Phase 3·psilocybin
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
VA Office of Research and Development
Major Depression
Not Yet Recruiting·Phase 1·psilocybin
Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
University of Wisconsin, Madison
Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·N/A·MDMA
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls
University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Yale University
Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·psilocybin
Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression
University of Washington
DepressionAnxiety
Not Yet Recruiting·Phase 2·ketamine
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
University of Rochester
Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Roswell Park Cancer Institute
Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·Phase 2·psilocybin
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
M.D. Anderson Cancer Center
PsilocybinNeuropathy
Not Yet Recruiting·N/A·Other
Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy
Fundacio Puigvert
AnesthesiaAnesthesia and Procedure Related Time IntervalsNephrectomy / Methods
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.