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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 913960 of 1728 trials
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence

University of Calgary

Post Traumatic Stress Disorder PTSDIntimate Partner Violence (IPV)
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)

NYU Langone Health

IBS - Irritable Bowel Syndrome
Not Yet Recruiting·Phase 4·Other

Examining Analgesic Synergy and Efficacy in Trauma Care

Wake Forest University Health Sciences

Opioid Use Disorder
Not Yet Recruiting·N/A·ketamine

Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation

Stanford University

Chronic PainKetamine
Not Yet Recruiting·Phase 3·psilocybin

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

VA Office of Research and Development

Major Depression
Not Yet Recruiting·N/A·Other

Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome

Hospital Clinic of Barcelona

Brugada Syndrome (BrS)Ventricular ArrhythmiaAnesthesia+1 more
Not Yet Recruiting·N/A·ketamine

Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study

Adriaan Dirk van der Wart

Post-Traumatic Stress Disorder
Not Yet Recruiting·Phase 1·LSD

Shortened LSD Intervention for Major Depressive Disorder

Johns Hopkins University

Major Depression ModerateMajor Depression SevereMajor Depression
Not Yet Recruiting·Phase 2·MDMA

MDMA Therapy in Veterans With PTSD

Sunstone Medical

Post Traumatic Stress Disorder
Not Yet Recruiting·Early Phase 1·Other

Transition From Acute to Chronic Opioid Use and Chronic Pain

Jacques E. Chelly

Opioid Use Disorder
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Johns Hopkins University

Mood (Psychological Function)Well BeingMood+1 more
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin After Trauma Surgery for Pain

Trent Emerick

Pain ManagementPostoperative Pain
Not Yet Recruiting·Phase 2·Other

Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery

Massachusetts General Hospital

Opoid ManagmentPain Management
Not Yet Recruiting·Phase 2·psilocybin

Study of Psilocybin Under Anesthesia Controlled by EEG

Stanford University

Major Depression
Not Yet Recruiting·Phase 2·ketamine

Ketamine HCl Prolonged Release Oral Tablets for CRPS

University of Southern California

Complex Regional Pain Syndromes
Not Yet Recruiting·Phase 1·psilocybin

Psilocybin as a Novel Therapy for Residual Anhedonia

NYU Langone Health

AnhedoniaEmotional Blunting
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin as a Treatment for Chronic Pain in Smokers

Yale University

Smokers With Chronic Pain
Not Yet Recruiting·Phase 2·ketamine

Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers

National Center for Complementary and Integrative Health (NCCIH)

Healthy Volunteers
Not Yet Recruiting·Early Phase 1·psilocybin

Psilocybin Administration With 5-HT1a Blockade

Johns Hopkins University

Psychedelic Effects in Healthy Volunteers
Not Yet Recruiting·N/A·Other

Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial

Centre Hospitalier Universitaire de Nice

Rotator Cuff InjuriesAnesthesia, GeneralArthroscopy
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

Brigham and Women's Hospital

Alcohol Use Disorder
Not Yet Recruiting·Phase 2·ketamine

Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)

Joshua Rosenblat

Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Not Yet Recruiting·Phase 3·psilocybin

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Centre Hospitalier Universitaire de Nīmes

Alcohol Use DisorderDepressive SympotomsPsilocybin
Not Yet Recruiting·Phase 1·psilocybin

Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

University of Wisconsin, Madison

Well-Being, PsychologicalPsychedelic Experiences
Not Yet Recruiting·Phase 2·psilocybin

Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression

University of Washington

DepressionAnxiety
Not Yet Recruiting·N/A·MDMA

Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls

University Hospital, Basel, Switzerland

Autism Spectrum Disorder
Not Yet Recruiting·Phase 2·ketamine

Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression

University of Rochester

Treatment Resistant Depression (TRD)Chronic Pain
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

Yale University

Chronic Low Back Pain (CLBP)Physical TherapyPsilocybin
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy as a Treatment for Depression

Washington University School of Medicine

Depression
Not Yet Recruiting·Phase 2·ketamine

Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse

University of Oklahoma

Head and Neck Cancer
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy

Emory University

PTSD
Not Yet Recruiting·N/A·Other

Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder

Shanghai Mental Health Center

Major Depressive Disorder (MDD
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

Roswell Park Cancer Institute

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Not Yet Recruiting·N/A·Other

Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy

Fundacio Puigvert

AnesthesiaAnesthesia and Procedure Related Time IntervalsNephrectomy / Methods
Not Yet Recruiting·N/A·LSD

Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)

Northern Jiangsu People's Hospital

Cirrhosis, LiverSplenectomy; StatusRenal Function Abnormal+1 more
Not Yet Recruiting·Phase 3·psilocybin

Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder

Lakshmi N Yatham

Bipolar II Depression
Not Yet Recruiting·Phase 1·Other

Opioid-free Anesthesia and Postoperative Delirium

Qianfoshan Hospital

Postoperative DeliriumGastrointestinal Tumors
Not Yet Recruiting·Phase 4·ketamine

Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal Thoughts

New York State Psychiatric Institute

Major Depressive Disorder (MDD)
Not Yet Recruiting·Phase 4·ketamine

Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities

University of Sao Paulo

Suicide PreventionKetamineCrisis Response Plan
Not Yet Recruiting·Phase 2·psilocybin

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Yale University

DepressionParkinson's Disease (PD)
Not Yet Recruiting·Phase 3·ketamine

InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression

Sunnybrook Health Sciences Centre

Treatment Resistant Depression
Not Yet Recruiting·Phase 1·MDMA

MDMA Assisted Therapy for BN

Icahn School of Medicine at Mount Sinai

Bulimia Nervosa
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD

Unity Health Toronto

Post Traumatic Stress DisorderPTSDChronic PTSD
Not Yet Recruiting·Phase 2·psilocybin

Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy

Kyle Greenway

Treatment-Resistant Major Depressive Disorder
Not Yet Recruiting·N/A·ketamine

A 2×2 Factorial Randomized Controlled Trial for ERCP

Gang Chen

Biliary and Pancreatic DiseasesEndoscopic Retrograde Cholangiopancreatography (ERCP)
Not Yet Recruiting·N/A·ketamine

Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery

Tanta University

ObesityPostoperative PainBariatric Surgery
Not Yet Recruiting·Phase 2·psilocybin

Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression

Centre for Addiction and Mental Health

Treatment-Resistant Depression
Not Yet Recruiting·Phase 2·ketamine

KALM-B: Ketamine-assisted Psychotherapy (KAP) to Lessen Morbidity After Burn Injury

Irma Fleming

PTSD and Trauma-related Symptoms
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.