Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy

About This Study

It is a prospective, randomized, controlled and superiority clinical trial, with the objective of comparing the effectiveness of multimodal anesthesia versus conventional anesthesia in patients undergoing oncological robotic nephrectomy within a short-stay surgery program (SSA). The effect of no specific drug will be evaluated, but rather the anesthetic approach ologies of surgical patients. The clinical trial will be carried out in a third-level university hospital, between the first half of 2026 and the second half of 2027 and, after approval by the corresponding Clinical Research Ethics Committee.

Conditions Studied

Interventions

• •Multimodal anesthesia
• •Conventional anesthesia

Eligibility

Inclusion Criteria:

* Patients ≥18 years.
* Indication for elective oncological robotic partial or radical nephrectomy.
* ASA classification I-III.
* Candidates for short-stay surgery according to institutional protocol.
* Signed informed consent.

Exclusion Criteria:

* Chronic opioid use. Defined as continuous opioid use during the 3 months prior to surgery
* Uncontrolled chronic pain. Defined as chronic pain not adequately controlled with usual treatment during the 3 months prior to surgery.
* Contraindications to NSAIDs, regional anesthesia, or drugs of the multimodal protocol.
* Advanced renal failure (GFR \<30 ml/min) at the preanesthetic visit.

Study Locations (1)