417 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145192 of 417 trials
Not Yet Recruiting·Phase 2·Other

PEX010-Assisted Therapy for Stimulant Use Disorder: A Safety, Feasibility and Efficacy Study

Filament Health Corp.

Stimulant Use Disorder
Not Yet Recruiting·Phase 3·DMT

Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)

University Hospital, Strasbourg, France

Relapsing-remitting Multiple Sclerosis (RRMS)
Not Yet Recruiting·N/A·Other

Acupressure's Impact on Pain and Physiological Parameters in Infants Undergoing Cardiac Catheterization

Baskent University

Cardiac Catheterization
Not Yet Recruiting·N/A·ketamine

Opioid Free Anesthesia Versus Opioid Based Anesthesia

Ain Shams University

Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·N/A·psilocybin

The Effects of Psilocybin on Shared Experience in Film Processing

Western University, Canada

Disorders of ConsciousnessPsychedelic Experiences
Not Yet Recruiting·Phase 1·Other

Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma

Assistance Publique Hopitaux De Marseille

MedulloblastomaEpendymoma
Not Yet Recruiting·Phase 2·psilocybin

Psilocybin-assisted Therapy for Alcohol Use Disorder

University of Sydney

Alcohol Use DisorderAlcohol DependenceDepression+1 more
Not Yet Recruiting·N/A·Other

Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients

Beijing Friendship Hospital

Opioid-Free AnesthesiaPOCDRecovery Quality+1 more
Not Yet Recruiting·Phase 4·ketamine

Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery

National Taiwan University Hospital

Head and Neck CancerAnesthesiaRenal Protection+2 more
Not Yet Recruiting·Phase 2·ketamine

Quelling of Excitotoxicity in Acute Stroke With Ketamine

Lower Merion Neurology Research Foundation

Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine

Ketamine Treatment for PTSD and MDD in TBI

Minneapolis Veterans Affairs Medical Center

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Phase 2·psilocybin

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P King

Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Recruiting·Early Phase 1·ketamine

Ketamine in Severe Traumatic Brain Injury

University of Texas Southwestern Medical Center

Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 1·psilocybin

A Study of Psychedelics in Healthy Older Adults With Low Well-being

Jennifer Mitchell

Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Phase 2·psilocybin

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

University of Washington

AnxietyDepressionHematopoietic and Lymphatic System Neoplasm+1 more
Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin

Subjective Experience Following Psilocybin

University of Calgary

Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 2·ketamine

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

Hospital Italiano de Buenos Aires

Depression DisorderKetamine
Recruiting·Phase 3·Other

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

Definium Therapeutics US, Inc.

Major Depressive Disorder
Recruiting·N/A·Other

An International Federated Model for Wearable-derived Remote Longitudinal Motor Monitoring in Young Children With Spinal Muscular Atrophy Compared With Healthy Controls: Active-NBS Study (UK)

University of Oxford

Spinal Muscular Atrophy (SMA)
Recruiting·Phase 1·psilocybin

Psilocybin to Treat Depression in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 1·psilocybin

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

University of New Mexico

PTSD
Recruiting·Phase 1·Other

Study of Midomafetamine in Healthy Adults

Resilient Pharmaceuticals

Healthy Volunteers
Recruiting·Phase 2·psilocybin

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Region Skane

Anorexia Nervosa
Recruiting·N/A·Other

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

Zeliha Alicikus

Critically IllIntubation ComplicationOxygenation+3 more
Recruiting·Early Phase 1·ketamine

Ketamine and Propofol NeuroImaging

Keith M Vogt

AnesthesiaPain
Recruiting·Phase 2·ketamine

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Mohsen Saidinejad

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·Early Phase 1·MDMA

MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital

Fibromyalgia
Recruiting·Phase 1·psilocybin

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

Gustavo Vazquez

DemoralizationSafety
Recruiting·Phase 1·psilocybin

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

University of Colorado, Denver

Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Early Phase 1·ketamine

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

University of Pennsylvania

Major Depressive Disorder (MDD)
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Recruiting·N/A·ketamine

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Massachusetts General Hospital

Treatment Resistant Depression (TRD)
Recruiting·Phase 1·DMT

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

University Hospital, Basel, Switzerland

5-methoxy-dimethyltryptamine (5-MeO-DMT)
Recruiting·N/A·ketamine

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Salma Health, Inc.

Depressed Mood
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Phase 2·ketamine

Ketamine for Veterans With Parkinson's Disease

VA Office of Research and Development

Parkinson's Disease
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·Phase 1·MDMA

MDMA-Assisted Therapy for Mental Healthcare Providers

Rachel Yehuda

Mental Wellbeing
Recruiting·Phase 1·psilocybin

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

StrokeChronic StrokeIntracerebral Haemorrhage+9 more
Recruiting·Phase 1·psilocybin

Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD

Suzanne "Sue" Sisley MD

PTSD
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Phase 2·Other

Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial

Unity Health Toronto

Chronic Neuropathic Pain
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.