414 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 145192 of 414 trials
Not Yet Recruiting·Phase 1·Other

Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma

Assistance Publique Hopitaux De Marseille

MedulloblastomaEpendymoma
Not Yet Recruiting·Phase 2·ketamine

Quelling of Excitotoxicity in Acute Stroke With Ketamine

Lower Merion Neurology Research Foundation

Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine

Ketamine Treatment for PTSD and MDD in TBI

Minneapolis Veterans Affairs Medical Center

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Early Phase 1·psilocybin

Psilocybin Administration With 5-HT1a Blockade

Johns Hopkins University

Psychedelic Effects in Healthy Volunteers
Recruiting·Phase 3·ketamine

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Recruiting·Phase 2·ketamine

Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)

Joshua Rosenblat

Borderline Personality Disorder (BPD)Treatment-Resistant Major Depressive DisorderTreatment-resistant Bipolar Depression+4 more
Recruiting·Phase 1·Other

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

Neutrolis

SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Recruiting·Early Phase 1·psilocybin

Psilocybin as a Treatment for Chronic Pain in Smokers

Yale University

Smokers With Chronic Pain
Recruiting·Phase 2·psilocybin

Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression

Centre for Addiction and Mental Health

Treatment-Resistant Depression
Recruiting·Early Phase 1·MDMA

MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital

Fibromyalgia
Recruiting·Phase 2·psilocybin

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P King

Post Traumatic Stress DisorderDepression - Major Depressive Disorder
Recruiting·Phase 2·psilocybin

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Yale University

DepressionParkinson's Disease (PD)
Recruiting·Phase 1·psilocybin

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Johns Hopkins University

Mood (Psychological Function)Well BeingMood+1 more
Recruiting·Phase 2·MDMA

MDMA-Assisted Massed Exposure Therapy for PTSD

Emory University

Post Traumatic Stress Disorder
Recruiting·Phase 2·MDMA

MDMA Therapy in Veterans With PTSD

Sunstone Medical

Post Traumatic Stress Disorder
Recruiting·Phase 3·psilocybin

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Centre Hospitalier Universitaire de Nīmes

Alcohol Use DisorderDepressive SympotomsPsilocybin
Recruiting·N/A·Other

Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial

Centre Hospitalier Universitaire de Nice

Rotator Cuff InjuriesAnesthesia, GeneralArthroscopy
Recruiting·Phase 3·Other

A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis

University Hospital, Montpellier

Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
Recruiting·Phase 1·psilocybin

A Study of Psychedelics in Healthy Older Adults With Low Well-being

Jennifer Mitchell

Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)
Recruiting·Early Phase 1·ketamine

Ketamine in Severe Traumatic Brain Injury

University of Texas Southwestern Medical Center

Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD

Unity Health Toronto

Post Traumatic Stress DisorderPTSDChronic PTSD
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

Sunstone Medical

Post Traumatic Stress DisorderPTSD
Recruiting·Phase 1·MDMA

MDMA Assisted Therapy for BN

Icahn School of Medicine at Mount Sinai

Bulimia Nervosa
Recruiting·Phase 2·MDMA

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

VA Office of Research and Development

Post Traumatic Stress DisorderAlcohol Use Disorder
Recruiting·Phase 1·psilocybin

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

Francisco A Moreno

Obsessive-Compulsive Disorder
Recruiting·Phase 2·psilocybin

Subjective Experience Following Psilocybin

University of Calgary

Investigating the Importance of the Subjective Psychedelic Experience
Recruiting·Phase 2·ketamine

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

Hospital Italiano de Buenos Aires

Depression DisorderKetamine
Recruiting·Phase 3·Other

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

Definium Therapeutics US, Inc.

Major Depressive Disorder
Recruiting·N/A·Other

Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy

Fundacio Puigvert

AnesthesiaAnesthesia and Procedure Related Time IntervalsNephrectomy / Methods
Recruiting·Phase 1·psilocybin

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

University of New Mexico

PTSD
Recruiting·N/A·Other

An International Federated Model for Wearable-derived Remote Longitudinal Motor Monitoring in Young Children With Spinal Muscular Atrophy Compared With Healthy Controls: Active-NBS Study (UK)

University of Oxford

Spinal Muscular Atrophy (SMA)
Recruiting·Phase 1·psilocybin

Psilocybin to Treat Depression in Spinal Cord Injury

James J. Peters Veterans Affairs Medical Center

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran
Recruiting·Phase 2·psilocybin

Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa

Region Skane

Anorexia Nervosa
Recruiting·N/A·Other

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

Zeliha Alicikus

Critically IllIntubation ComplicationOxygenation+3 more
Recruiting·N/A·ketamine

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Massachusetts General Hospital

Treatment Resistant Depression (TRD)
Recruiting·Early Phase 1·ketamine

Ketamine and Propofol NeuroImaging

Keith M Vogt

AnesthesiaPain
Recruiting·Phase 1·psilocybin

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

University of Colorado, Denver

Healthy VolunteerOlder Adults (65-85 Years)
Recruiting·Early Phase 1·ketamine

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

University of Pennsylvania

Major Depressive Disorder (MDD)
Recruiting·Phase 1·psilocybin

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

Gustavo Vazquez

DemoralizationSafety
Recruiting·Phase 2·ketamine

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Mohsen Saidinejad

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·Phase 1·DMT

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

University Hospital, Basel, Switzerland

5-methoxy-dimethyltryptamine (5-MeO-DMT)
Recruiting·N/A·ketamine

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Salma Health, Inc.

Depressed Mood
Recruiting·Early Phase 1·psilocybin

Psilocybin for Prolonged Grief Disorder

University of Virginia

Prolonged Grief Disorder
Recruiting·Phase 1·MDMA

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

University Hospital, Basel, Switzerland

Healhty
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·N/A·LSD

Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD

University Hospital, Basel, Switzerland

LSD Reaction
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Early Phase 1·ketamine

The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.

National and Kapodistrian University of Athens

Opioid-Refractory Chronic Cancer-Related Pain
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.