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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 577624 of 1728 trials
Completed·Phase 2·ketamine

Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder

Pouya Movahed Rad

Depressive Disorder, Major
Completed·Early Phase 1·ketamine

Ketamine Infusion for Social Anxiety Disorder

Yale University

Social Anxiety Disorder
Completed·Phase 1·ketamine

Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

VA Office of Research and Development

Major Depressive DisorderAlcohol Use Disorder
Completed·Early Phase 1·ketamine

A Multimodal Neuroimaging Study of Brain Activation Patterns Under Ketamine

Psychiatric University Hospital, Zurich

Major Depressive Disorder
Completed·Phase 1·ketamine

A Study to Evaluate the Absolute Bioavailability of Intranasal and Oral Esketamine and the Effects of Clarithromycin on the Pharmacokinetics of Intranasal Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·N/A·Other

Neuropathic Evaluation of Postoperative Pain

Rennes University Hospital

Neuropathic Pain Evaluation
Completed·Phase 4·ketamine

Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain

VA Pittsburgh Healthcare System

Acute PainChronic PainHernia+2 more
Completed·Phase 4·ketamine

Ketamine For Acute Treatment of Pain in Emergency Department

The Brooklyn Hospital Center

Pain
Completed·Phase 4·ketamine

A Comparison of the Sedation During Endoscopy in Children

Kanuni Sultan Suleyman Training and Research Hospital

Failed Moderate Sedation During Procedure
Completed·Phase 4·ketamine

Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy

University of Manitoba

Obstructive Sleep Apnea Syndrome
Completed·N/A·MDMA

Effects of MDMA on Emotional and Social Memories

University of Chicago

Healthy
Completed·Phase 1·ketamine

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult Participants

Janssen Research & Development, LLC

Healthy
Completed·Early Phase 1·LSD

Neuronal Correlates of Altered States of Consciousness

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·ketamine

Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)

Massachusetts General Hospital

Treatment Resistant Depression
Completed·Phase 2·ketamine

Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction

iX Biopharma Ltd.

Pain
Completed·N/A·ketamine

Evaluating Ketamine and Psychological Sequelae

Defense and Veterans Center for Integrative Pain Management

Pain, Ketamine Infusion, Psychologic Sequelae
Completed·Phase 2·ketamine

Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy

NYU Langone Health

PainPostoperative Depression
Completed·N/A·ketamine

Cognitive Biases Under Ketamine

Centre Hospitalier St Anne

Healthy Subjects
Completed·Phase 2·ketamine

Ketamine for Depression and Suicide Risk

Mayo Clinic

DepressionSuicide
Completed·Phase 1·Other

Abuse Liability and Human Pharmacology of Mephedrone

Parc de Salut Mar

Amphetamine-Related Disorders
Completed·Phase 2·ketamine

Ketamine in Adolescents With Treatment-Resistant Depression

University of Minnesota

Major Depressive Disorder
Completed·N/A·ketamine

Ketamine's Actions on Rumination Mechanisms as an Antidepressant

King's College London

Remission in Depression
Completed·Phase 1·ketamine

Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·Other

Opioid Free Anesthesia: What About Patient Comfort?

Université Libre de Bruxelles

Anesthesia
Completed·N/A·ketamine

Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers

National Taiwan University

Substance Use Disorders
Completed·Phase 4·ketamine

A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion

NYU Langone Health

Postoperative Pain
Completed·N/A·ketamine

Effects of Propofol and Ketofol on Core Body Temperature in MRI

Istanbul University

Children
Completed·N/A·ketamine

Retrospective Evaluation of Ketamine Effectiveness for the Treatment of Acute Battlefield Related Pain

Defense and Veterans Center for Integrative Pain Management

Pain, AcuteAnalgesiaAmputation, Traumatic+2 more
Completed·Phase 1·ketamine

Single Dose Administration of Ketamine 10, 20, 40 and 80 mg and 5 mg Solution for Infusion in 15 Healthy Subjects

University Medicine Greifswald

Healthy
Completed·Phase 2·ketamine

A Study to Assess the Analgesic Properties of a Sublingual Wafer Formulation of Ketamine Following Third Molar Extraction

Lotus Clinical Research, LLC

Pain
Completed·Phase 3·ketamine

Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department

University of British Columbia

Emergency Department Procedural SedationFracture Reduction
Completed·Phase 1·ketamine

Biomarkers of Fast Acting Therapies in Major Depression

University of California, Los Angeles

Major Depressive Disorder
Completed·Phase 1·ketamine

A Study to Evaluate the Effect of Intranasal Esketamine on Cognitive Functioning in Healthy Subjects

Janssen Research & Development, LLC

Healthy
Completed·N/A·ketamine

Pre-Emptive Analgesia in Ano-Rectal Surgery

University of Vermont

HemorrhoidsFissure in AnoRectal Fistula+1 more
Completed·Phase 2·psilocybin

A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence

NYU Langone Health

Alcohol Dependence
Completed·Phase 1·psilocybin

UW Psilocybin Pharmacokinetics Study

University of Wisconsin, Madison

Healthy
Completed·Phase 1·ketamine

Study to Assess the Effects of Allergic Rhinitis and Co-administration of Mometasone or Oxymetazoline on the Pharmacokinetics, Safety, and Tolerability of Intranasal Esketamine

Janssen Research & Development, LLC

Allergic Rhinitis
Completed·Phase 2·ketamine

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·Phase 4·ketamine

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Rigshospitalet, Denmark

Postoperative PainChronic PainAnalgesics
Completed·Phase 1·psilocybin

Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators

Johns Hopkins University

Healthy
Completed·Phase 4·ketamine

Biomarker Assessment of Glutamatergic Target Engagement

New York State Psychiatric Institute

Healthy Controls
Completed·Phase 2·MDMA

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

Resilient Pharmaceuticals

Social Anxiety in Autistic Adults
Completed·N/A·ketamine

Effects of Ketamine on Eye Movements, Perception and Brain Function

University of Bonn

Functional Neuroimaging
Completed·N/A·ketamine

Plasma Concentration of Ketamine and Norketamine .

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Chronic Pain
Completed·Phase 4·ketamine

Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric

Universitas Diponegoro

Specified SedativeHypnotic
Completed·Phase 1·Other

Effects of Hallucinogens and Other Drugs on Mood and Performance

Johns Hopkins University

Healthy
Completed·Phase 2·ketamine

Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial

Mayo Clinic

Critical Illness
Completed·Phase 1·ketamine

Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study

University of Calgary

PainTraumatic Limb Injury
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.