417 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 529576 of 1728 trials
Completed·Phase 2·ketamine

IN Sub-Dissociative Ketamine vs IN Fentanyl

Wake Forest University Health Sciences

Bone Fracture
Completed·N/A·Other

Opioid Free Anesthesia in Thoracic Surgery

Medical University of Silesia

Thoracic SurgeryAnalgesics, OpioidAnesthesia, Conduction
Completed·Phase 1·ketamine

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Janssen Research & Development, LLC

Hepatic ImpairmentNormal Hepatic Function
Completed·Phase 1·ketamine

Memory Modulation by Pain During Anesthesia

University of Pittsburgh

AmnesiaPainAnesthesia
Completed·N/A·Other

Correlates of Anxiety Associated With a Life-threatening Illness

Resilient Pharmaceuticals

Anxiety
Completed·Phase 4·DMT

Tecfidera and the Gut Microbiota

Biogen

Multiple Sclerosis, Relapsing-Remitting
Completed·N/A·ketamine

Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery

Milton S. Hershey Medical Center

Obesity
Completed·Phase 1·LSD

A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers

Eleusis Therapeutics

Healthy
Completed·Phase 3·ketamine

A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Completed·Phase 3·ketamine

Ketamine for Treatment Resistant Late-Life Depression

VA Office of Research and Development

Treatment Resistant Depressive Disorder
Completed·N/A·Other

Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies

Children's Hospital of Michigan

Conscious Sedation
Completed·Phase 2·Other

A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy

iX Biopharma Ltd.

Acute Pain
Completed·Phase 2·ketamine

intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery Pain

Assiut University

Postoperative Pain
Completed·Phase 1·ketamine

Pharmacokinetic Study of Intranasal Esketamine and Its Effects on the Pharmacokinetics of Orally-Administered Midazolam and Bupropion in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 4·ketamine

Ketamine Infusion for Adolescent Depression and Anxiety

Yale University

Major Depressive DisorderAnxiety Disorder
Completed·Phase 4·ketamine

Effects of Low-dose Ketamine as an Adjunct to Propofol-based Anesthesia for Electroconvulsive Therapy

University of Alberta

Depressive Disorder
Completed·Phase 3·ketamine

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression

Janssen Research & Development, LLC

Treatment-resistant Depression
Completed·Phase 2·ketamine

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

Mayo Clinic

Cognitive DisordersDeliriumAcute Kidney Injury
Completed·Phase 4·ketamine

Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

Medical College of Wisconsin

Wounds and InjuriesRib Fractures
Completed·N/A·LSD

A Prospective Non-therapeutic Study in Patients Diagnosed With Niemann-Pick Disease Type C

ZevraDenmark

Niemann-Pick Disease, Type C
Completed·Phase 3·ketamine

A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depressive Disorder, Treatment-Resistant
Completed·Phase 3·ketamine

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Treatment-resistant Depression
Completed·Phase 3·ketamine

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Treatment-resistant Depression
Completed·Phase 3·Other

Efficacy Study Comparing Compounded Topical Pain Creams vs. Placebo for Treating Pain Symptoms

Walter Reed National Military Medical Center

Pain
Completed·Phase 2·ketamine

Local Ketamine Instillation for Postoperative Analgesia

Assiut University

Postoperative Pain
Completed·Phase 4·Other

Natalizumab in Preventing Post-partum Relapses in Multiple Sclerosis

State University of New York at Buffalo

Multiple Sclerosis
Completed·N/A·ketamine

Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression

The Cleveland Clinic

Treatment Resistant DepressionMajor Depressive DisorderSevere Depression
Completed·N/A·Other

Heart Rate Variability in Depression

Emory University

Major Depressive Disorder
Completed·Phase 1·ketamine

Spreading Depolarization and Ketamine Suppression

University of New Mexico

Cortical Spreading DepolarizationCortical Spreading DepressionSubarachoid Hemorrhage+1 more
Completed·Phase 1·LSD

A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

Eleusis Therapeutics

Healthy Volunteers
Completed·N/A·ketamine

Prospective Analgesic Compound Efficacy (PACE) Study

Express Specialty Pharmacy

ArthritisTendonitisGout+5 more
Completed·Phase 2·ketamine

Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD)

Icahn School of Medicine at Mount Sinai

Posttraumatic Stress Disorder (PTSD)
Completed·Phase 2·MDMA

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

Resilient Pharmaceuticals

Anxiety
Completed·Phase 1·ketamine

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Minneapolis Veterans Affairs Medical Center

Depressive Disorder, Treatment-ResistantStress Disorders, Post-Traumatic
Completed·Phase 2·psilocybin

Psilocybin-facilitated Treatment for Cocaine Use

University of Alabama at Birmingham

Cocaine-Related Disorders
Completed·Phase 2·ketamine

miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome

University of Alabama at Birmingham

Major Depressive Disorder
Completed·N/A·ketamine

Ketamine: Comparison of IV Push vs. IV Drip

Antonios Likourezos

Pain
Completed·Phase 2·ketamine

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

VA Office of Research and Development

Treatment-resistant Depression
Completed·Phase 1·psilocybin

The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Religious Professionals

NYU Langone Health

Religious or Spiritual Problem
Completed·Early Phase 1·ketamine

Ketamine for Depression Relapse Prevention Following ECT

St Patrick's Hospital, Ireland

Depression
Completed·Phase 3·ketamine

Effects of Ketamine in the Acute Phase of Suicidal Ideation

Centre Hospitalier Universitaire de Nīmes

Suicidal Ideation
Completed·Phase 2·ketamine

Intranasal Ketamine as a Sedative for Venipuncture

Hospital de Clinicas de Porto Alegre

Respiratory Tract DiseaseAcute PainDiseases of the Digestive System
Completed·Phase 1·psilocybin

Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

Johns Hopkins University

Healthy
Completed·N/A·DMT

Dancing for Better Aging: Evaluating the Impact of a Dance/Movement Therapy (D/MT) Program for Older Adults

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Aging
Completed·N/A·LSD

The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers

Psychiatric University Hospital, Zurich

Healthy
Completed·Phase 1·ketamine

Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)

New York State Psychiatric Institute

Obsessive-Compulsive Disorder
Completed·Phase 1·ketamine

Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Intravenous Ketamine

Yale University

Depression
Completed·N/A·ketamine

Ketamine and fMRI for Neuropathic Pain

University Health Network, Toronto

Neuralgia
PreviousPage 12 of 36Next

Browse by Condition

View all conditions →

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.