Effects of S-ketamine on Perioperative Opioid Consumption

About This Study

This study is a triple-blind randomized controlled trial conducted at a tertiary care hospital in Brussels. It investigates whether a single dose of S-ketamine can reduce opioid (morphine) consumption in the first 24 hours after elective laparoscopic gynecological surgery in relatively healthy adult patients (ASA 1-2). The goal is to assess S-ketamine's effectiveness within a standardized postoperative pain management protocol.

Conditions Studied

Interventions

• •Esketamine at low dose
• •Saline (0.9% NaCl)

Eligibility

Inclusion Criteria:

* Adult patients American Society of Anesthesiologists (ASA) physical status classification I or II
* Scheduled for elective laparoscopic gynecological surgery

Exclusion Criteria:

* Body mass index (BMI) \> 30 kg/m²
* Known allergy to any drugs used in the study
* Chronic pain patients or regular use of analgesics
* Pregnant or breastfeeding patients

Study Locations (1)