Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder
Dr. med. Marcus Herdener
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
Neuronetics
Investigation to Understand and Optimize Psilocybin
Charles Raison
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
Queen's University
ACT_for Alcohol Use Disorder and Depression
Centre hospitalier de l'Université de Montréal (CHUM)
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Centre for Addiction and Mental Health
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
LSD to Improve Cluster Headache Impact Trial
Radboud University Medical Center
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
Nantes University Hospital
Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)
University of Twente
Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
Johns Hopkins University
Understanding and Treating Suicidal Ideation With Ketamine
The Royal's Institute of Mental Health Research
Psilocybin for Methamphetamine Addiction
Kevin Murnane
Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy Subjects
University Hospital, Basel, Switzerland
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Centre for Addiction and Mental Health
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
University Hospital, Basel, Switzerland
Tolerability of MDMA in Schizophrenia
Anya Bershad, MD, PhD
Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers
MoCA Clinic and Institute
Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans
Deepak C. D'Souza
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
Unity Health Toronto
Digital Intervention for Psychedelic Preparation (DIPP): Comparing Meditation and Music-Based Programs
University College, London
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
McMaster University
Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine
Assistance Publique - Hôpitaux de Paris
Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
Icahn School of Medicine at Mount Sinai
Intravenous Ketamine for Treatment-Resistant Depression
Mayo Clinic
MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder
Patricia Suppes
Investigation of Psychedelic Effects in Psychoactive Substances
Johns Hopkins University
Non-steroidal Anti-inflammatory Drugs in Pleurodesis
Centre Hospitalier Universitaire, Amiens
State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
Baylor College of Medicine
The ENHANCE Study: taVNS and Psilocybin
University of Wisconsin, Madison
Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls
University Hospital, Basel, Switzerland
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
Yale University
Pragmatic Trial of Psilocybin Therapy in Palliative Care
Charles S. Grob, M.D.
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
University of California, San Diego
Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression
Icahn School of Medicine at Mount Sinai
Psilocybin rTMS for Treatment Resistant Depression
University of Texas at Austin
Psychedelic-assisted Group Program for First Responders
Empower Research Inc
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
Cybin IRL Limited
Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Unity Health Toronto
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest
Christian Hassager
Safety for Home Administration of Microdose Psilocybin Use
Johns Hopkins University
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.