417 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 193240 of 417 trials
Recruiting·Phase 2·LSD

LSD Treatment for Persons With Alcohol Use Disorder

Felix Mueller

Alcohol Use Disorder (AUD)
Recruiting·Phase 1·ketamine

Pilot Study of RR-HNK in OCD

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

The Ketamine Research Foundation

Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Recruiting·Phase 1·psilocybin

RCT of Psilocybin-assisted CBT for Depression

University of California, Los Angeles

Major Depressive Diorder
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Alan Davis

Lung Non-Small Cell CarcinomaUnipolar Depression
Recruiting·Phase 3·psilocybin

Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)

Bruyère Health Research Institute.

Psychological Distress
Recruiting·Phase 2·psilocybin

Psilocybin on Brain Mechanisms of Motivation in OUD

University of Pennsylvania

Opioid Use Disorder
Recruiting·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder (OUD)

NYU Langone Health

Opioid Use Disorder
Recruiting·Phase 3·psilocybin

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Cybin IRL Limited

Major Depressive Disorder (MDD)Depression in AdultsDepression - Major Depressive Disorder+3 more
Recruiting·Phase 2·MDMA

A Phase 2A Trial of DT402 for Autism Spectrum Disorder

Definium Therapeutics US, Inc.

Autism Spectrum DisorderASD
Recruiting·Phase 2·ketamine

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

VA Office of Research and Development

Chronic Low Back PainDepression
Recruiting·Phase 2·ketamine

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

ACADIA Pharmaceuticals Inc.

Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Recruiting·Phase 1·psilocybin

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

Medical University of Vienna

Depression - Major Depressive DisorderAnhedonia
Recruiting·Phase 1·psilocybin

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

University of California, Berkeley

Aging
Recruiting·Phase 2·psilocybin

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

University of British Columbia

Opioid DependenceChronic Pain
Recruiting·Phase 2·psilocybin

Wellcome Leap Psilocybin for OUD

Anna Rose Childress, Ph.D.

Opioid Use Disorder
Recruiting·Early Phase 1·psilocybin

PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm

Imperial College London

Self Harm
Recruiting·N/A·Other

Supra Inguinal Fascia Iliaca Block as Rescue Analgesia Following Total Hip Arthroplasty

Institut Mutualiste Montsouris

Hip Arthroplasty, TotalPost Operative Pain, AcuteNerve Block
Recruiting·N/A·ketamine

Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression

Hospital Universitari Vall d'Hebron Research Institute

Depression - Major Depressive DisorderDepression DisorderDepression Chronic+1 more
Recruiting·Phase 1·psilocybin

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Johns Hopkins University

Posttraumatic Stress Disorder
Recruiting·N/A·ketamine

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

University General Hospital of Patras

Magnesium SulfateRemifentanilS 100beta+6 more
Recruiting·Phase 2·MDMA

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·N/A·ibogaine

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

University of California, Irvine

Opioid Use Disorder (OUD)
Recruiting·Phase 2·MDMA

MDMA in Borderline Personality Disorder

Yale University

Borderline Personality Disorder
Recruiting·N/A·ketamine

Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery

University Medical Centre Ljubljana

Orofacial CleftsCleft Lip and PalateAlveolar Ridge Defect
Recruiting·Phase 2·psilocybin

Psilocybin-Assisted Therapy for Intergenerational Trauma

Rachel Yehuda

Psychological StressDepressionAnxiety
Recruiting·Phase 2·psilocybin

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

NYU Langone Health

Alcohol Use Disorder
Recruiting·Phase 3·ketamine

Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures

State University of New York at Buffalo

Distal Radius Fracture ReductionPain ControlPediatric Fractures
Recruiting·Phase 1·psilocybin

The RECAP2 Study: Midazolam and Psilocybin

University of Wisconsin, Madison

Psilocybin
Recruiting·N/A·DMT

Antidepressant Response of DMT Masked With Propofol

University Hospital, Basel, Switzerland

Major Depressive DisorderPsychedelic Experiences
Recruiting·Phase 1·DMT

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Yale University

Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Recruiting·N/A·Other

Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study

University Hospital Dubrava

Major Abdominal SurgeriesMechanical Ventilation
Recruiting·Phase 2·psilocybin

Mindfulness-assisted Psychedelic Therapy

University of Southern California

Mental Health
Recruiting·Phase 4·ketamine

Magnesium and Cramping

Corewell Health East

Uterine CrampsPostoperative Pain ManagementHysteroscopy
Recruiting·Phase 1·ketamine

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

Juliana Zambrano, MD, MPH

Depression
Recruiting·Phase 3·ketamine

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Università Vita-Salute San Raffaele

Major Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 2·psilocybin

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

The University of Texas Health Science Center, Houston

Bipolar II DisorderDepression, BipolarSuicidality
Recruiting·Phase 2·ketamine

A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients

Mayo Clinic

Depression
Recruiting·Phase 2·ketamine

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Northwestern University

Posttraumatic HeadachePosttraumatic Stress Disorder
Recruiting·Phase 2·psilocybin

Psilocybin Therapy for Psychological Distress in Palliative Patients

University Medical Center Groningen

COPD (Chronic Obstructive Pulmonary Disease)ALS (Amyotrophic Lateral Sclerosis)MS (Multiple Sclerosis)+2 more
Recruiting·Early Phase 1·LSD

Drug Effects on Mood and Behavior - Expectancy

University of Chicago

LSD
Recruiting·Phase 2·psilocybin

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

University of Iowa

Alcohol Use DisorderAlcohol DependenceAlcohol Abuse
Recruiting·Early Phase 1·LSD

Mood Effects of Serotonin Agonists: Depression

University of Chicago

LSDMajor Depressive DisorderDepression
Recruiting·Phase 2·MDMA

Dose Optimization of MDMA-Assisted Therapy for PTSD

Bronx VA Medical Center

Posttraumatic Stress Disorder
Recruiting·Phase 2·psilocybin

Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

Nathan Brashares Sackett

Alcohol Use Disorder (AUD)PTSD
Recruiting·Phase 2·ketamine

Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder

Dr. med. Marcus Herdener

Alcohol Abuse/DependenceAlcohol Use Disorder (AUD)Alcoholism
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.