Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
The Effects of Psilocybin on Shared Experience in Film Processing
Western University, Canada
Psilocybin-assisted Therapy for Alcohol Use Disorder
University of Sydney
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies
University of Washington
Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
Francisco A Moreno
Subjective Experience Following Psilocybin
University of Calgary
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
Psilocybin to Treat Depression in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Psilocybin for Prolonged Grief Disorder
University of Virginia
Safety and Preliminary Efficacy of Organic Whole Psilocybin-Containing Mushrooms to Treat Patients Suffering From PTSD
Suzanne "Sue" Sisley MD
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
RCT of Psilocybin-assisted CBT for Depression
University of California, Los Angeles
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Alan Davis
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
Bruyère Health Research Institute.
Psilocybin on Brain Mechanisms of Motivation in OUD
University of Pennsylvania
Psilocybin for Opioid Use Disorder (OUD)
NYU Langone Health
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
Medical University of Vienna
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
Wellcome Leap Psilocybin for OUD
Anna Rose Childress, Ph.D.
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Imperial College London
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Johns Hopkins University
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
The RECAP2 Study: Midazolam and Psilocybin
University of Wisconsin, Madison
Mindfulness-assisted Psychedelic Therapy
University of Southern California
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
Investigation to Understand and Optimize Psilocybin
Charles Raison
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
Queen's University
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
University Hospital, Basel, Switzerland
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Centre for Addiction and Mental Health
Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
Johns Hopkins University
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.