Psychedelic Clinical Trials
Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Centre for Addiction and Mental Health
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
NYU Langone Health
Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)
Centre Hospitalier St Anne
Psilocybin Administration With 5-HT1a Blockade
Johns Hopkins University
Psilocybin as a Treatment for Chronic Pain in Smokers
Yale University
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
Centre for Addiction and Mental Health
Mindfulness-based Psilocybin Therapy for PTSD
Anthony P King
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Johns Hopkins University
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Yale University
Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms
Centre Hospitalier Universitaire de Nīmes
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
Unity Health Toronto
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
Sunstone Medical
Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
Francisco A Moreno
Subjective Experience Following Psilocybin
University of Calgary
Psilocybin to Treat Depression in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder
University of New Mexico
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
Region Skane
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Gustavo Vazquez
Psilocybin for Prolonged Grief Disorder
University of Virginia
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
Bruyère Health Research Institute.
RCT of Psilocybin-assisted CBT for Depression
University of California, Los Angeles
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Alan Davis
Psilocybin on Brain Mechanisms of Motivation in OUD
University of Pennsylvania
Psilocybin for Opioid Use Disorder (OUD)
NYU Langone Health
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
Medical University of Vienna
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
University of British Columbia
Wellcome Leap Psilocybin for OUD
Anna Rose Childress, Ph.D.
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Imperial College London
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Johns Hopkins University
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
NYU Langone Health
The RECAP2 Study: Midazolam and Psilocybin
University of Wisconsin, Madison
Mindfulness-assisted Psychedelic Therapy
University of Southern California
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
University Health Network, Toronto
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The University of Texas Health Science Center, Houston
Psilocybin Therapy for Psychological Distress in Palliative Patients
University Medical Center Groningen
Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial
University of Iowa
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
Nathan Brashares Sackett
A Randomized Neuroimaging Trial of Psilocybin in Depression
Sunnybrook Health Sciences Centre
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Yale University
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
University of Calgary
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
Mechanistic Studies of Psilocybin in Headache Disorders
Yale University
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View all conditions →How to Join a Clinical Trial
Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.
1. Review
Read the trial details, eligibility criteria, and what participation involves.
2. Contact
Reach out to the study team using the contact information provided.
3. Screen
Complete the screening process to determine if you're eligible.