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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 16331680 of 1728 trials
Unknown·N/A·ketamine

Proper Dosage of Ketamine in Intravenous Regional Anesthesia

University Health Network, Toronto

Pain.
Withdrawn·Phase 2·ketamine

Ketamine and Midazolam Infusions for CRPS: Feasibility Study

Stanford University

Complex Regional Pain Syndromes
Withdrawn·Phase 2·psilocybin

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Johns Hopkins University

Opioid Use Disorder
Withdrawn·N/A·ketamine

Prospective Study of Induction Medications Used in the Trauma RSI

University of Southern California

TraumaRapid Sequence Intubation
Withdrawn·Phase 2·psilocybin

Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies

University of New Mexico

Suicidal Ideation
Withdrawn·Phase 4·ketamine

Ketamine in Central Sensitization

University Hospitals Cleveland Medical Center

EndometriosisChronic Pelvic Pain
Withdrawn·Phase 2·MDMA

A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders

Resilient Pharmaceuticals

Anorexia Nervosa Restricting TypeBinge-Eating Disorder
Withdrawn·Phase 2·ketamine

The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series

Washington University School of Medicine

Postpartum Depression
Withdrawn·Phase 2·ibogaine

Trifecta Research Study

Johns Hopkins University

PTSD - Post Traumatic Stress DisorderCognitive DysfunctionBrain Trauma+1 more
Withdrawn·Phase 1·ketamine

The Dreamy Jet Study

University of Wisconsin, Madison

SedationBlood Drawing ProcedureImmunization+1 more
Withdrawn·Phase 2·MDMA

MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents

University of California, Los Angeles

PTSD, Post Traumatic Stress DisorderAdolescentsPsychotherapy
Withdrawn·Phase 1·ketamine

Repeated Neurocognitive Measurements in Depressed Patients

Jay Fournier

Depression, Unipolar
Withdrawn·Phase 1·psilocybin

Safety and Tolerability of Psilocybin in Post-Traumatic Stress Disorder

Johns Hopkins University

Post-Traumatic Stress Disorder
Withdrawn·Phase 3·Other

A Study to Evaluate the Efficacy and Safety of REL-1017 As Adjunctive Treatment of Major Depressive Disorder (MDD)

MGGM LLC

Major Depressive Disorder (MDD)
Withdrawn·Phase 1·MDMA

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Resilient Pharmaceuticals

Psychological Effects of Study Drug
Withdrawn·N/A·psilocybin

Optimizing Microdosing and Meditation

National University of Natural Medicine

MeditationMicrodosing
Withdrawn·Phase 1·MDMA

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

Yale University

Post Traumatic Stress Disorder
Withdrawn·Phase 2·psilocybin

Psilocybin for Major Depressive Disorder

Washington University School of Medicine

Major Depressive Disorder
Withdrawn·Phase 3·ketamine

INK Feasibility Study

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Procedural Sedation
Withdrawn·Phase 1·ketamine

Connectivity Changes Associated With Ketamine Assisted Psychotherapy for PTSD

University of New Mexico

PTSD
Withdrawn·Phase 2·psilocybin

Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use

Johns Hopkins University

Opioid Use Disorder
Withdrawn·Early Phase 1·ketamine

Ketamine-Assisted PsychoTherapy ViAbility in Treating Cancer-related Emotional Distress

Northwell Health

Cancer-related Problem/ConditionDepressive SymptomsAnxiety Disorders
Withdrawn·Phase 4·ketamine

VA Aripiprazole vs Esketamine for Treatment Resistant Depression

VA Office of Research and Development

Depressive Disorder, Major
Withdrawn·Phase 2·ketamine

Ketamine for the Treatment for Alcohol Use Disorder in the ED

Brigham and Women's Hospital

Alcohol Use Disorder
Withdrawn·Phase 4·ketamine

Remifentanil Plus Ketamine for Dynamic Flexible Bronchoscopy

Beth Israel Deaconess Medical Center

Bronchoscopy
Withdrawn·Phase 2·MDMA

Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans

Resilient Pharmaceuticals

PTSD
Withdrawn·N/A·ketamine

Electroencephalographic (EEG) Profils for Patients on Intravenous Ketamine.

Assistance Publique - Hôpitaux de Paris

Neuropathic Pain
Withdrawn·Early Phase 1·psilocybin

Exploratory Study of Low Dose Psilocybin

University of Alabama at Birmingham

Demoralization
Withdrawn·Phase 2·psilocybin

PET Synaptogenesis After Psilocybin In DEpression Recovery

Washington University School of Medicine

Major Depressive DisorderAnhedonia
Withdrawn·Phase 1·psilocybin

Bioavailability Study of Psilocybin in Normal Adults

University of Wisconsin, Madison

Healthy
Withdrawn·Phase 2·ketamine

Pilot Study of Ketamine Sedation for Aneurysmal Subarachnoid Hemorrhage

Jenna L Leclerc MD, PhD

Subarachnoid Hemorrhage, Aneurysmal
Withdrawn·Phase 4·Other

Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium

University of Miami

Covid19Hyperactive DeliriumPneumonia, Viral
Withdrawn·Phase 2·ketamine

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study

Zylorion Health

Treatment Resistant Major Depressive Disorder
Withdrawn·Early Phase 1·ketamine

Scheduled Intranasal Ketamine

Sanford Health

PainTrauma
Withdrawn·Phase 2·psilocybin

Effect of SSRIs on Response to Psilocybin Therapy

Cybin Therapeutics Inc.

DepressionMajor Depressive DisorderMild Depression+2 more
Withdrawn·Early Phase 1·psilocybin

Mood and Cognitive Effects of Psilocybin in Healthy Participants

Optimi Health Corporation

Mood DisturbanceMood ChangeSleep Disturbance+7 more
Withdrawn·Phase 1·ketamine

A Study in Healthy Men to Test Whether BI 474121 Can Reverse the Memory Problems Caused by Ketamine

Boehringer Ingelheim

Healthy
Withdrawn·Phase 2·ketamine

Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial

Northwell Health

Cancer of Head and NeckMucositis OralPharyngeal Mucositis
Withdrawn·Phase 2·psilocybin

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Treatment Resistant MDD

Massachusetts General Hospital

Treatment-Resistant Major Depressive Disorder
Withdrawn·N/A·Other

Opioid-free Total Hip Arthroplasty

Johns Hopkins University

Hip Osteoarthritis
Withdrawn·Phase 4·ketamine

Preoperative Ketamine and Perioperative Depression

Northwestern University

Depressive Disorder
Withdrawn·Phase 1·ketamine

A Study to Assess Feasibility of Using Clinician-directed and Digital Application Supported Cognitive Behavior Therapy (CBT) in Conjunction With Esketamine in Participants With Treatment-resistant Depression

Janssen Research & Development, LLC

Depression
Withdrawn·Phase 2·MDMA

Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Resilient Pharmaceuticals

Posttraumatic Stress Disorder
Withdrawn·Phase 2·ketamine

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

Wake Forest University Health Sciences

Radical Prostatectomies
Withdrawn·N/A·Other

Personality and Drug Use (PDU)

Quantified Citizen Technologies Inc.

Personality
Withdrawn·Phase 2·ketamine

Intramuscular Ketamine for Suicidal Ideation

Icahn School of Medicine at Mount Sinai

Suicidal Ideation
Withdrawn·Phase 2·ketamine

Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures

The University of Texas Health Science Center, Houston

Pain, Acute
Withdrawn·Phase 4·ketamine

Bubiket Study: Ultrasound Guided Fascia Iliaca Nerve Block With Bupivacaine and Adjuvant Ketamine vs. Bupivacaine Alone

Antonios Likourezos

Pain, Musculoskeletal
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.