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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 577624 of 1021 trials
Not Yet Recruiting·Phase 3·ketamine

Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain

Tehran University of Medical Sciences

PainDigital Block
Not Yet Recruiting·Phase 1·ketamine

Ketamine Biomarker Validation

Soterix Medical

Treatment Resistant Depression (TRD)
Not Yet Recruiting·Phase 4·ketamine

Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT(ESSENCE)

Chinese PLA General Hospital

Postoperative Pain
Not Yet Recruiting·Phase 4·ketamine

Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial

Assiut University

Varicocelectomy
Not Yet Recruiting·Phase 4·ketamine

Ketamine for the Treatment of Refractory Status Epilepticus

Thomas Jefferson University

Refractory Status Epilepticus
Not Yet Recruiting·Phase 3·ketamine

Ketamine Sedation in the ICU (KANINE) RCT

McMaster University

Mechanical VentilationCritically Ill Intensive Care Unit Patients
Not Yet Recruiting·Phase 1·ketamine

Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD

Queen's University

Chronic PainPosttraumatic Stress Disorder (PTSD)
Not Yet Recruiting·Phase 3·ketamine

Comparison of Esketamine Nasal Spray vs.Aripiprazole in Treat.Resistant Major Depressive Disorder in Elderly Patients

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Depressive Disorder
Not Yet Recruiting·N/A·ketamine

Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy

IVO JURISIC

Obese PatientsBariatric Surgical PainBariatric Surgery (Sleeve Gastrectomy )+6 more
Not Yet Recruiting·N/A·ketamine

Effect of Different Drugs on Emergency Delirium in Preschool Age Patient

Zagazig University

Emergence Delirium, Anesthesia
Not Yet Recruiting·N/A·ketamine

Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children

Anqing Municipal Hospital

EtomidateEsketamineTonsillectomy+1 more
Not Yet Recruiting·Phase 4·ketamine

Ketamine for Postherpetic Neuralgia With Depression

Huazhong University of Science and Technology

Depression DisordersHerpetic Neuralgia
Not Yet Recruiting·Early Phase 1·ketamine

Ketamine and Lidocaine Infusion in Refractory Chronic Migraine

Assiut University

Refractory Chronic Migraine
Not Yet Recruiting·Phase 3·ketamine

Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents

Federal University of São Paulo

Depressive DisorderSuicidal Ideas
Not Yet Recruiting·Early Phase 1·ketamine

Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients

University of Zurich

Depressive Symptoms Mild to Moderate in SeverityAnxietyQuality of Life (QOL)+2 more
Not Yet Recruiting·Phase 4·ketamine

Feasibility of Closed-loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine

bo xu

General Anesthesia With PropofolClosed-Loop
Not Yet Recruiting·Phase 1·ketamine

Ketamine for Combined Depression and Alcohol Use Disorder

University Hospital of North Norway

DepressionAlcohol Use Disorder
Not Yet Recruiting·N/A·ketamine

Opioid Free Anesthesia Versus Opioid Based Anesthesia

Ain Shams University

Opioid Free AnesthesiaLaparoscopic Bariatric Surgeries
Not Yet Recruiting·Phase 4·ketamine

Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery

National Taiwan University Hospital

Head and Neck CancerAnesthesiaRenal Protection+2 more
Not Yet Recruiting·Phase 2·ketamine

Quelling of Excitotoxicity in Acute Stroke With Ketamine

Lower Merion Neurology Research Foundation

Acute Ischemic Stroke
Not Yet Recruiting·Phase 2·ketamine

Ketamine Treatment for PTSD and MDD in TBI

Minneapolis Veterans Affairs Medical Center

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury
Recruiting·Early Phase 1·ketamine

Ketamine in Severe Traumatic Brain Injury

University of Texas Southwestern Medical Center

Traumatic Brain InjuryTraumatic Encephalopathy
Recruiting·Phase 2·ketamine

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

Hospital Italiano de Buenos Aires

Depression DisorderKetamine
Recruiting·Early Phase 1·ketamine

Ketamine and Propofol NeuroImaging

Keith M Vogt

AnesthesiaPain
Recruiting·Early Phase 1·ketamine

Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

University of Pennsylvania

Major Depressive Disorder (MDD)
Recruiting·Phase 2·ketamine

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

Mohsen Saidinejad

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more
Recruiting·N/A·ketamine

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Massachusetts General Hospital

Treatment Resistant Depression (TRD)
Recruiting·N/A·ketamine

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Salma Health, Inc.

Depressed Mood
Recruiting·Phase 3·ketamine

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

University of Virginia

Status Epilepticus
Recruiting·Phase 1·ketamine

Prospective IR-led Sedation Feasibility

CAMC Health System

AnesthesiaSedation and AnalgesiaInterventional Radiology
Recruiting·Phase 2·ketamine

Ketamine for Veterans With Parkinson's Disease

VA Office of Research and Development

Parkinson's Disease
Recruiting·Phase 2·ketamine

Ketamine for Opioid Use Disorder

University of Maryland, Baltimore

Opioid Use Disorder
Recruiting·Phase 1·ketamine

Pilot Study of RR-HNK in OCD

Carolyn Rodriguez

Obsessive-Compulsive Disorder
Recruiting·Phase 2·ketamine

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

The Ketamine Research Foundation

Phantom Limb Syndrome With Pain
Recruiting·Phase 3·ketamine

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Janssen Research & Development, LLC

Depressive Disorder, Major
Recruiting·Phase 2·ketamine

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

VA Office of Research and Development

Chronic Low Back PainDepression
Recruiting·Phase 2·ketamine

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

ACADIA Pharmaceuticals Inc.

Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
Recruiting·Phase 4·ketamine

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center

Orthopedic Trauma Surgery PatientsPostoperative PainOpioid Use+2 more
Recruiting·N/A·ketamine

Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression

Hospital Universitari Vall d'Hebron Research Institute

Depression - Major Depressive DisorderDepression DisorderDepression Chronic+1 more
Recruiting·N/A·ketamine

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

University General Hospital of Patras

Magnesium SulfateRemifentanilS 100beta+6 more
Recruiting·N/A·ketamine

Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery

University Medical Centre Ljubljana

Orofacial CleftsCleft Lip and PalateAlveolar Ridge Defect
Recruiting·Phase 3·ketamine

Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures

State University of New York at Buffalo

Distal Radius Fracture ReductionPain ControlPediatric Fractures
Recruiting·Phase 4·ketamine

Magnesium and Cramping

Corewell Health East

Uterine CrampsPostoperative Pain ManagementHysteroscopy
Recruiting·Phase 1·ketamine

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

Juliana Zambrano, MD, MPH

Depression
Recruiting·Phase 3·ketamine

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Università Vita-Salute San Raffaele

Major Depressive DisorderTreatment Resistant Depression
Recruiting·Phase 2·ketamine

A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients

Mayo Clinic

Depression
Recruiting·Phase 2·ketamine

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Northwestern University

Posttraumatic HeadachePosttraumatic Stress Disorder
Recruiting·N/A·ketamine

Music as an Adjunct to Ketamine Therapy for Chronic Pain

McGill University

Chronic PainChronic Noncancer Pain
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.