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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 673720 of 1728 trials
Completed·Phase 1·MDMA

Influence of Bupropion on the Effects of MDMA

University Hospital, Basel, Switzerland

HealthySubstance-related Disorders
Completed·N/A·ketamine

Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation

Inje University

Psychomotor Agitation
Completed·Phase 1·ketamine

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

Biogen

Schizophrenia
Completed·Phase 2·ketamine

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine

Isfahan University of Medical Sciences

Closed Multiple Fractures of Upper and Lower Limbs
Completed·Phase 4·ketamine

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

HealthPartners Institute

Pain
Completed·Phase 1·ketamine

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 2·ketamine

A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion

NYU Langone Health

Spinal Fusion
Completed·Phase 4·Other

Natalizumab Temporary Discontinuation Study

University at Buffalo

Multiple Sclerosis
Completed·Phase 4·ketamine

Intra-nasal Ketamine for Analgesia in the Emergency Department

Lions Gate Hospital

Pain
Completed·Phase 1·ketamine

Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department

Rhode Island Hospital

Pain
Completed·Phase 2·ketamine

A Study of Ketamine in Patients With Treatment-resistant Depression

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·N/A·ketamine

Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris

University of Washington

Monitoring, Intraoperative
Completed·Phase 1·ketamine

Changes in Striatal [11C]ORM-13070 Binding Elicited by Changing Levels of Endogenous Noradrenaline

University of Turku

Changes in Striatal [11C]ORM-13070 Binding.
Completed·Early Phase 1·MDMA

Effects of MDMA and Methylphenidate on Social Cognition

University Hospital, Basel, Switzerland

Social Cognition
Completed·Phase 2·ketamine

Low Dose Ketamine VR Analgesia During Burn Care Procedure

National Institute of General Medical Sciences (NIGMS)

Burn
Completed·N/A·Other

Analysis of Lymphocyte Cell Surface Adhesion Marker Expression in Natalizumab Population With Active Control

John F. Foley, MD

Multiple Sclerosis
Completed·Phase 2·ketamine

A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression

Janssen Research & Development, LLC

Major Depressive Disorder
Completed·N/A·ketamine

PET Imaging of mGLuR5 With Drug Challenge

Yale University

Major Depressive DisorderPost-Traumatic Stress Disorder (PTSD)
Completed·Phase 4·ketamine

Ketamine in the Treatment of Suicidal Depression

New York State Psychiatric Institute

Major Depressive DisorderSuicidal Ideation
Completed·Phase 2·ketamine

Study of NMDA Antagonists and Neuropathic Pain

University Hospital, Clermont-Ferrand

Neuropathic Pain
Completed·Phase 4·ketamine

Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions

Baskent University

Conscious Sedation Failure During Procedure
Completed·N/A·ketamine

Treatment of Suicidal Ideation With Intravenous Ketamine Infusion

University of Alabama at Birmingham

DepressionSuicidal Ideation
Completed·N/A·ketamine

Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation

Pr Isabelle CONSTANT

PainAnesthesia
Completed·Phase 4·ketamine

The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients

TC Erciyes University

Renal Function DisorderHemodynamic Instability
Completed·N/A·ketamine

Treatment Resistant Depression (Pilot)

Washington University School of Medicine

Depressive Disorder, Treatment-Resistant
Completed·N/A·ketamine

Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children

Washington University School of Medicine

AbscessFracture
Completed·Phase 4·ketamine

Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults

Centre Hospitalier Universitaire de Nice

FractureDislocation
Completed·N/A·ketamine

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

Massachusetts General Hospital

Major Depressive Disorder
Completed·Phase 1·ketamine

A Study of LY2979165 and LY2140023 in Healthy Volunteers

Eli Lilly and Company

Healthy Volunteers
Completed·Phase 1·ketamine

Ketamine for Depression and Alcohol Dependence

Yale University

DepressionAlcohol Dependence
Completed·Phase 3·ketamine

Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks

University Hospital, Grenoble

Major Depressive Disorder
Completed·Phase 4·ketamine

Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department

Brooke Army Medical Center

Abdomen, AcuteOther Acute PainFlank Pain+2 more
Completed·Phase 1·ketamine

A Multiple Ascending Dose Study of BCI-838 in Healthy Volunteers

BrainCells Inc.

Healthy
Completed·Phase 2·ketamine

Ketamine in the Treatment of Depression

Columbia University

Major Depressive Disorder
Completed·N/A·Other

Characterization of the Prosocial and Prosexual Effects of GHB

University of Zurich

Depressive Disorder, MajorBipolar DisorderAutistic Disorder
Completed·Phase 2·ketamine

Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash

Aaron Cumpston, PharmD, BCOP

Mucositis
Completed·N/A·ketamine

The Pre-Emptive Administration Of Ketamine for Controlling Post-thoracotomy Pain

University of Campania Luigi Vanvitelli

Post Thoracotomy Pain
Completed·Phase 4·ketamine

A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients

Jiangsu Nhwa Pharmaceutical Co., Ltd.

Efficacy and Safety of Mivacurium Chloride for Pediatric Patients
Completed·Phase 4·ketamine

Ketamine For Suicidal Ideation

James Murrough

Suicidal Ideation
Completed·N/A·DMT

Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients

Merck KGaA, Darmstadt, Germany

Relapsing Multiple Sclerosis
Completed·Phase 2·ketamine

Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

Fundació Sant Joan de Déu

Progressive Infantile Idiopathic Scoliosis
Completed·Phase 2·psilocybin

Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

University of New Mexico

Alcohol Dependence
Completed·Phase 4·ketamine

Preventing Pain After Heart Surgery

Barts & The London NHS Trust

PainHyperalgesiaChronic Illness+1 more
Completed·Phase 1·MDMA

Emotional Effects of Methylphenidate and MDMA in Healthy Subjects

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·Other

A Real-World Study of Clinical Use of Available Treatments for Pediatric Patients With Spinal Muscular Atrophy

Novartis Pharmaceuticals

Muscular Atrophy, Spinal
Completed·Phase 4·Other

Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting in Bariatric Surgery

Coastal Anesthesiology Consultants

Postoperative Nausea and Vomiting
Completed·N/A·Other

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

Baylor College of Medicine

Mediastinal LymphadenopathiesMediastinal MassesHilar Lymphadenopathies
Completed·N/A·ketamine

Intranasal Ketamine in Treatment-Resistant Depression

James Murrough

Major Depressive Disorder
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Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.