417 Recruiting Now

Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 289336 of 1728 trials
Completed·N/A·Other

Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial

Brno University Hospital

Anaesthesia Induction
Completed·Phase 3·LSD

Sodium Lactate and Brain Relaxation (LSD)

Centre Hospitalier Universitaire de Besancon

Sodium LactateIntracranial HypertensionBrain Relaxation
Completed·Early Phase 1·ketamine

Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty

Dartmouth-Hitchcock Medical Center

Pain, PostoperativeArthroplasty Complications
Completed·Phase 3·MDMA

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Resilient Pharmaceuticals

Posttraumatic Stress Disorder
Completed·N/A·ketamine

Efficacy of Ketamine in Post Anesthesia Recovery Room

University of Alberta

Pain, PostoperativeKetamine Adverse ReactionPain, Refractory+2 more
Completed·Phase 3·ketamine

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder

Janssen-Cilag International NV

Depressive Disorder, Major
Completed·Phase 1·ketamine

Low-Dose Ketamine in Children With ADNP Syndrome

Alexander Kolevzon

ADNP Syndrome
Completed·N/A·ketamine

Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression

Mclean Hospital

Major Depressive Disorder
Completed·Phase 2·psilocybin

The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

COMPASS Pathways

Treatment Resistant Depression
Completed·Phase 3·Other

Opiate Suicide Study in Patients With Major Depression

Stanford University

Major Depressive Disorder
Completed·N/A·Other

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

COMPASS Pathways

Treatment Resistant Depression
Completed·Phase 1·ketamine

Phase 1 Bioavailability Study of MELT-100 (Midazolam and Ketamine Sublingual) and IV Midazolam or Ketamine

Melt Pharmaceuticals

Healthy Volunteers
Completed·N/A·Other

Characterization of Altered Waking States of Consciousness in Healthy Humans

University of Zurich

Altered Waking States of Consciousness in Healthy Humans
Completed·Phase 4·ketamine

Low Dose Ketamine and Acute Pain Crisis

Rhode Island Hospital

Sickle Cell Crisis
Completed·Phase 4·ketamine

Ketamine for Acute Pain Management After Trauma

The University of Texas Health Science Center, Houston

Trauma InjuryPainOpioid Use
Completed·Phase 2·MDMA

Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

MAPS Europe B.V.

PTSD
Completed·Phase 2·ketamine

Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric Surgery

University Hospital of Split

Surgical Procedure, Unspecified
Completed·Phase 1·ketamine

A Study of Different Oral Thin Film (S)-Ketamine Formulations for Sublingual Administration in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·Phase 2·psilocybin

Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients

University of Zurich

Alcohol Use Disorder
Completed·Phase 1·psilocybin

Comparative Acute Effects of LSD, Psilocybin and Mescaline

University Hospital, Basel, Switzerland

Healthy
Completed·N/A·Other

Impact of Fingolimod Adherence on Outcomes

Novartis Pharmaceuticals

Multiple Sclerosis
Completed·Phase 4·ketamine

A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health

Field Trip Health

DepressionAnxietyPost Traumatic Stress Disorder
Completed·N/A·ketamine

Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine

Charite University, Berlin, Germany

Emotions
Completed·Phase 1·ketamine

A Study of Sublingually Administered (S)-Ketamine Oral Solution in Healthy Participants

Janssen Research & Development, LLC

Healthy
Completed·N/A·Other

Patient Doctor Lies

University of Utah

Patient LyingPrivacy StatementsRisk Statements+2 more
Completed·N/A·DMT

Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)

Delphinus Medical Technologies, Inc.

Breast Cancer DetectionDense Breast ParenchymaBenign Breast Findings+2 more
Completed·Phase 4·ketamine

Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy

Medical University of Warsaw

ObesityPostoperative PainPostoperative Nausea+2 more
Completed·N/A·ketamine

Ketamine Infusion as Sedative Analgesic in Severe ARDS

Interfaith Medical Center

Intensive Care Unit SyndromeMechanical Ventilation ComplicationSedatives and Hypnotics Causing Adverse Effects in Therapeutic Use+1 more
Completed·Phase 2·psilocybin

A Study of Psilocybin for Major Depressive Disorder (MDD)

Usona Institute

Depressive Disorder, Major
Completed·Phase 3·ketamine

Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery

Christine Oryhan

Opioid Use, UnspecifiedBariatric Surgery CandidateAnesthesia
Completed·Early Phase 1·ketamine

The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women

The Ketamine Research Foundation

KetamineLactation
Completed·N/A·ketamine

Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control

CHRISTUS Health

Abdominal Pain
Completed·N/A·ketamine

A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders

Medical University of Gdansk

Treatment Resistant DepressionBipolar DepressionKetamine+1 more
Completed·N/A·ketamine

Chart Review of Patients Undergoing Ketamine Infusions

Brain and Cognition Discovery Foundation

Major Depressive DisorderBipolar DisorderObsessive-Compulsive Disorder+1 more
Completed·Phase 1·ketamine

Effect of Ketamine Intranasal Spray in Treatment of Chronic Cluster Headache

CCH Pharmaceuticals

Cluster Headache
Completed·Phase 3·Other

Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use

Prisma Health-Upstate

Opioid Use
Completed·N/A·Other

Validation of a Shared Decision-Making Tool for Multiple Sclerosis

Shared Decision Making Resources

Multiple Sclerosis
Completed·Phase 1·DMT

Clinical Study of GH001 in Depression

GH Research Ireland Limited

Treatment Resistant DepressionMajor Depressive DisorderDepression
Completed·Phase 2·LSD

LSD Therapy for Persons Suffering From Major Depression

University Hospital, Basel, Switzerland

Major Depressive Disorder
Completed·Phase 4·Other

IPACK Study in Total Knee Arthroplasty Patients

University Health Network, Toronto

Knee Replacement Arthroplasty
Completed·Phase 4·ketamine

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

MercyOne Des Moines Medical Center

DepressionDepression SevereDepression Acute+2 more
Completed·Early Phase 1·MDMA

Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction

University Hospital, Basel, Switzerland

Healthy
Completed·Phase 2·ketamine

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

Grace Lim, MD, MS

Obstetric PainPostpartum DepressionBreastfeeding+5 more
Completed·Early Phase 1·ketamine

EEG Characteristics in ECT

University of New Mexico

Electroconvulsive TherapyDirect Current ElectroencephalogramKetamine+1 more
Completed·Phase 1·ketamine

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

University of Minnesota

Post-Traumatic Stress DisordersMajor Depressive Disorder
Completed·Phase 1·ketamine

THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis

Yale University

CannabisKetamine
Completed·Phase 2·ketamine

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Clexio Biosciences Ltd.

Adjunctive Treatment of Major Depressive Disorder
Completed·Phase 3·ketamine

Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy

University of Patras

Lung DiseasesDiagnosisAnesthesia
PreviousPage 7 of 36Next

Browse by Condition

View all conditions →

How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.