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Psychedelic Clinical Trials

Find clinical trials studying psilocybin, MDMA, ketamine and other psychedelics. Many trials are actively recruiting participants who haven't found relief from conventional treatments.

Showing 14411488 of 1728 trials
Terminated·Phase 1·ketamine

Pharmacokinetics of Low Dose Ketamine Infusion

University of Texas Southwestern Medical Center

SedationOpioid Tolerance
Terminated·Phase 4·ketamine

Hematoma Block as an Adjunct to Procedural Sedation for Forearm Fracture Reduction

Rhode Island Hospital

Forearm Fracture
Terminated·Phase 4·ketamine

The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery

Glostrup University Hospital, Copenhagen

Pain, Postoperative
Terminated·N/A·ketamine

Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function

University of Saskatchewan

Colorectal Cancer
Terminated·Phase 4·ketamine

Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease

Children's Hospital of Philadelphia

Sickle Cell Disease
Terminated·Phase 3·ketamine

Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine

Assistance Publique - Hôpitaux de Paris

CancerMucositis
Unknown·N/A·Other

B-cell Depletion in Offspring to Women With MS Under Immunomodulatory Treatment

Region Stockholm

Multiple SclerosisB-Cell DeficiencyOffspring, Adult+2 more
Unknown·Phase 4·ketamine

Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia

Assiut University

Post Cesarean Analgesia
Unknown·Phase 3·Other

Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context

Dr George Medvedev

MigraineChronic Migraine
Unknown·N/A·Other

Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease

Fondation Hôpital Saint-Joseph

Procedural PainCongenital Heart DiseaseHeart Surgery+1 more
Unknown·Early Phase 1·ketamine

Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting

Alexandria University

Procedural Sedation
Unknown·N/A·ketamine

ED50 of Esketamine for Laser Treatment in Children

Air Force Military Medical University, China

Anesthesia
Unknown·N/A·Other

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Jagiellonian University

Analgesics, OpioidAnesthesia, EndotrachealAnesthesia, General
Unknown·N/A·Other

Opioid Free Anaesthesia Versus Opioid Based Anesthesia for Laparscopic Cholecystectomy

Al-Azhar University

Opioid Use
Unknown·N/A·ketamine

Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy

The Second Hospital of Anhui Medical University

Depressive Symptoms
Unknown·Phase 2·psilocybin

Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD

Apex Labs Ltd.

Post-traumatic Stress DisorderDepression
Unknown·N/A·ketamine

Ketamine and Dexmedetomidine Comparative Study

Sohag University

Post Operative Pain
Unknown·N/A·DMT

Effect of eHealth on AB Use of Children With Acute, Uncomplicated URTIs

Max Nieuwdorp

Upper Respiratory Tract Infection
Unknown·Phase 4·Other

A Prospective Study on the Comparison of Postoperative Pain According to the Use of Cocktail Therapy in Laminoplasty

Kyunghee University Medical Center

Adverse Effects in the Therapeutic Use of Analgesic, Antipyretic and Anti-Inflammatory Drug, Unspecified
Unknown·Phase 2·ketamine

Prevention of Shivering Associated With Spinal Anesthesia

Assiut University

Shivering, Spinal Anesthesia
Unknown·Early Phase 1·ketamine

Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent Patients

Henan Provincial People's Hospital

Anxiety-depression
Unknown·Phase 1·ayahuasca

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

Advanced Integrative Medical Science Institute

Major DepressionPost Traumatic Stress Disorder
Unknown·Phase 4·ketamine

Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery

AXIS Spine Center- a division of Northwest Specialty Hospital

Revision Spine SurgeryFusion of SpineCervical Fusion+1 more
Unknown·Phase 1·psilocybin

Northwest Therapies Trauma Psilocybin Study Compassionate Use Study

NWTraumatherapies

Trauma, Nervous System
Unknown·Early Phase 1·psilocybin

A Community of Practice Program With Psilocybin-assisted Therapy for End-of-Life Patients

The Roots to Thrive Society for Psychedelic Therapy

End of Life
Unknown·N/A·ketamine

Effect of Quadratus Lumborum Block With Compound Lidocaine and Esketamine on Pain After Colorectal Surgery

Tianjin Medical University General Hospital

Postoperative Pain
Unknown·N/A·ketamine

Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study

Sohag University

Post Operative Sore Throat
Unknown·Phase 4·mescaline

Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis

Xiangya Hospital of Central South University

Lupus Nephritis
Unknown·N/A·ketamine

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

Stella Center

Post-Traumatic Stress DisorderTraumatic Brain Injury
Unknown·Early Phase 1·ketamine

Effect of Subanesthetic Dose Esketamine on Propofol-refentanil Closed-loop Targeted Controlled Infusion

bo xu

Esketamine
Unknown·Phase 2·MDMA

Preliminary Effectiveness of Individual and Group MDMA-assisted Therapy for Israeli Veterans With PTSD and Moral Injury.

HaEmek Medical Center, Israel

Post Traumatic Stress DisorderMoral InjuryMDMA ('Ecstasy')
Unknown·Phase 2·psilocybin

Evaluation of Psilocybin-assisted Psychotherapy (PaP) for the Treatment of Post-traumatic Stress Disorder (PTSD) in Military Veterans

Combat Stress

PTSD
Unknown·Phase 3·ketamine

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation

University of Ottawa

Suicidal Ideation
Unknown·Early Phase 1·ketamine

Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery

Assiut University

Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Unknown·N/A·Other

Enhanced vs.Standard Pain Management of Patients at Risk for Chronic Post-surgical Pain

University Hospital, Geneva

Chronic Post Surgical Pain
Unknown·N/A·ketamine

Application of Different Modes of Esketamine Administration in Pediatric Day Circumcision

Yangzhou University

Pain
Unknown·N/A·ketamine

Median Effective Dose of Esketamine Pretreatment to Prevent Sufentanil-induced Cough

Yangzhou University

SufentanilEsketamine
Unknown·Phase 4·ketamine

Adductor Canal Block in Total Knee Arthroplasty

Assiut University

Analgesia
Unknown·N/A·ketamine

Comparison of Analgesic and Sedative Effects of Esmketamine and Remifentanil Combined With Propofol Respectively in Septic Shock Patients With Invasive Mechanical Ventilation

The First Hospital of Jilin University

Patients With Septic Shock Admitted to the ICU on Invasive Mechanical Ventilation
Unknown·Phase 1·LSD

The Effect of LSD on Neural Synchrony, Prosocial Behavior, and Relationship Quality

Maastricht University

Prosocial Behavior
Unknown·Phase 4·ketamine

An EEG Study of Intravenous Ketamine for Major Depression Disorder

Ehave Inc.

Major Depressive Disorder
Unknown·Phase 1·ketamine

KetaMoHydBup: Pharmacokinetic Interaction of S-ketamine, Morphine, Hydromorphone and Buprenorphine

Elina Brinck

The Effect of S-ketamine on Pharmacokinetics of Morphine, Hydromorphone, and Buprenorphine
Unknown·N/A·ketamine

Tolerance Assesment of the Usage of an Analgesic Dose of Esketamine for Treatment of Moderate to Intense Pain in an Emergency Departement

Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences

Pain, Acute
Unknown·N/A·ketamine

Analgesic Effect of Esketamine in DCSB in Adultscontrolled Study

Shenzhen Second People's Hospital

AnalgesiaBurns
Unknown·N/A·ketamine

Opioid Sparing Anesthesia in Cervical Spine Surgery

Evangelismos Hospital

Pain, PostoperativePain, AcutePain, Chronic+6 more
Unknown·N/A·Other

Personality and Drug Use

Psychedelic Data Society

No Conditions Study Focus on Substance Use and Personality
Unknown·N/A·ketamine

Auditory MMN EEG in TRD in Response to Ketamine

Unity Health Toronto

Treatment-resistant Depression (TRD)
Unknown·Phase 2·psilocybin

Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder

Halucenex Life Sciences Inc.

Treatment Resistant DisordersPost Traumatic Stress Disorder
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How to Join a Clinical Trial

Clinical trials are research studies that test new treatments. Participating can give you access to cutting-edge therapies while contributing to medical science. Each trial has specific eligibility criteria based on the research goals.

1. Review

Read the trial details, eligibility criteria, and what participation involves.

2. Contact

Reach out to the study team using the contact information provided.

3. Screen

Complete the screening process to determine if you're eligible.